推薦產品
化驗
>99% (HPLC)
形狀
powder
包裝
pkg of 1 × 1 mg (699851P-1mg)
pkg of 1 × 5 mg (699851P-5mg)
製造商/商標名
Avanti Research™ - A Croda Brand 699851P
應用
vaccine development
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
O[C@H]([C@@H](CO[C@@H]([C@@H]1NC(C[C@H](OC(CCCCCCCCCCCCC)=O)CCCCCCCCCCC)=O)O[C@H](CO)[C@@H](OP([O-])(O)=O)[C@@H]1O)O[C@H](O)[C@@H]2NC(C[C@H](O)CCCCCCCCCCC)=O)[C@@H]2O.[NH4+]
一般說明
Monophosphoryl lipid A (MPLA) is an analog of the lipid A moiety. It is regarded as a detoxified derivative of the lipopolysaccharide (LPS).
生化/生理作用
Monophosphoryl lipid A (MPLA) is a natural agonist for the toll-like receptor-4 (TLR4). It is useful as an adjuvant in immunization. MPLA is a safe prophylactic agent and has immunotherapeutic applications. It induces tumor necrosis factor and interleukin (IL)-1β, however not as efficient as lipopolysaccharide (LPS). MPLA improves immune response during bacterial sepsis infection.
包裝
2 mL Amber Glass Crimp Cap Vial (699851P-1mg)
2 mL Amber Glass Crimp Cap Vial (699851P-5mg)
其他說明
For R&D use only. Not for drug, household, or other uses.
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
No data available
閃點(°C)
No data available
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
客戶也查看了
Specific features of human monocytes activation by monophosphoryl lipid A
Scientific reports, 8(1), 1-13 (2018)
Monophosphoryl lipid A induces protection against LPS in medullary thick ascending limb through a TLR4-TRIF-PI3K signaling pathway
American Journal of Physiology: Renal Physiology, 313(1), F103-F115 (2017)
The TLR4 agonist monophosphoryl lipid a drives broad resistance to infection via dynamic reprogramming of macrophage metabolism
Journal of Immunology, 200(11), 3777-3789 (2018)
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