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Key Documents

QBD10776

Sigma-Aldrich

dPEG®48-biotin acid

>90% (HPLC)

同義詞:

Biotin-PEG-acid, Biotin-PEG48-COOH, PEG2000 biotin acid, PEG48-biotin acid

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About This Item

經驗公式(希爾表示法):
C112H218N4O53S
分子量::
2500.99
分類程式碼代碼:
12352106
NACRES:
NA.22

化驗

>90% (HPLC)

形狀

solid or viscous liquid

反應適用性

reaction type: Biotinylations
reaction type: Pegylations

聚合物結構

shape: linear
functionality: monofunctional

運輸包裝

ambient

儲存溫度

−20°C

特點和優勢

dPEG48 biotin acid is a 2,500 Dalton biotin acid product that contains a 157 atom (187.8 Å) dPEG spacer. Amphiphilic dPEG48 biotin acid dissolves in water or aqueous buffer and organic solvents. It does not cause aggregation or precipitation of biomolecules. Using 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) chemistry, dPEG48 biotin acid couples to free primary amines in aqueous media. These free amines can be on a protein, peptide, or the treated surface of a nanoparticle. Moreover, the terminal propionic acid moiety can be functionalized with other reactive groups for coupling directly to surfaces such as glass, gold, or magnetic nanoparticles. dPEG48 biotin acid is a monodisperse equivalent of the polymeric PEG2000.

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法律資訊

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Thurid Boetel et al.
Biochemical and biophysical research communications, 349(1), 296-302 (2006-08-29)
The biological function of prion protein (PrP) and the physiological relevance of its truncated subtypes and glycoforms is still enigmatic. In this paper, we adduce evidence that recombinant murine PrP fragment 90-231 (mPrP90-231) contains a biotin-mimicking sequence motif that causes
Alexander Kuzmin et al.
Bioconjugate chemistry, 21(11), 2076-2085 (2010-10-23)
The utility of catalyst-free azide-alkyne [3 + 2] cycloaddition for the immobilization of a variety of molecules onto a solid surface and microbeads was demonstrated. In this process, the surfaces are derivatized with aza-dibenzocyclooctyne (ADIBO) for the immobilization of azide-tagged

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