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Key Documents

QBD10007

Sigma-Aldrich

Biotin-dPEG®24-TFP ester

同義詞:

Polyethylene glycol

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About This Item

經驗公式(希爾表示法):
C67H117F4N3O28S
分子量::
1520.71
分類程式碼代碼:
12352108
PubChem物質ID:
NACRES:
NA.22

化驗

>90%

形狀

solid or viscous liquid

反應適用性

reaction type: Biotinylations
reaction type: Biotinylations
reactivity: amine reactive

reagent type: cross-linking reagent

聚合物結構

shape: linear
functionality: monofunctional

運輸包裝

ambient

儲存溫度

−20°C

SMILES 字串

O=C(CCCCC1SCC(N2)C1NC2=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(OC3=C(C(F)=CC(F)=C3F)F)=O

特點和優勢

The Biotin-dPEG®24-TFP ester has 2,3,5,6-tetrafluorophenyl (TFP) moiety which hydrolyze more slowly than NHS esters in aqueous media and are more reactive towards amines than NHS esters. The single molecular weight Biotin-dPEG®24-TFP ester has a long spacer of precise length (99.3 Å) between the biotin moiety and the labeled molecule. This dPEG spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the dPEG spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.

法律資訊

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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