跳轉至內容
Merck
全部照片(3)

Key Documents

P0256

Sigma-Aldrich

吡啶硫胺 氢溴酸盐

~95%, crystalline

同義詞:

1-([4-氨基-2-甲基]-5-嘧啶基甲基)-2-甲基-3-(β-羟乙基)溴化吡啶鎓, 新吡啶硫胺

登入查看組織和合約定價


About This Item

經驗公式(希爾表示法):
C14H18N4O · 2HBr
CAS號碼:
分子量::
420.14
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

~95%

形狀

crystalline

顏色

off-white to yellow

儲存溫度

2-8°C

SMILES 字串

Br.[Br-].Cc1ncc(C[n+]2cccc(CCO)c2C)c(N)n1

InChI

1S/C14H19N4O.2BrH/c1-10-12(5-7-19)4-3-6-18(10)9-13-8-16-11(2)17-14(13)15;;/h3-4,6,8,19H,5,7,9H2,1-2H3,(H2,15,16,17);2*1H/q+1;;/p-1

InChI 密鑰

DMVBWVASDWGFNH-UHFFFAOYSA-M

一般說明

吡啶硫胺氢溴酸盐是一种杂环化合物合成砌块,由于能够模拟硫胺素缺乏症且可能用于开发具有实用药理特性的新化合物,因而成为重要的有机合成和药物化学工具。

應用

吡啶硫胺氢溴酸盐可用作合成焦磷酸吡硫胺的前体。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

未看到正確版本?

如果您需要一個特定的版本,您可以透過批號來尋找特定憑證。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Darren Navarro et al.
Journal of neurochemistry, 106(2), 603-612 (2008-04-16)
Thiamine deficiency provides an effective model of selective neuronal cell death. (1)H and (13)C-NMR was used to investigate the effects of thiamine deficiency on the synthesis of amino acids derived from [1-(13)C]glucose in vulnerable (medial thalamus; MT) compared to non-vulnerable
Joseph M Hall et al.
Frontiers in neuroscience, 12, 773-773 (2018-11-18)
Exercise has been shown to improve or rescue cognitive functioning in both humans and rodents, and the augmented actions of neurotrophins within the hippocampus and associated regions play a significant role in the improved neural plasticity. The septohippocampal circuit is
Qipeng Zhang et al.
Neurobiology of aging, 32(1), 42-53 (2009-02-24)
Thiamine pyrophosphate (TPP) and the activities of thiamine-dependent enzymes are reduced in Alzheimer's disease (AD) patients. In this study, we analyzed the relationship between thiamine deficiency (TD) and amyloid precursor protein (APP) processing in both cellular and animal models of
Jessica J Roland et al.
Neurobiology of learning and memory, 87(1), 123-132 (2006-09-19)
A rodent model of diencephalic amnesia, pyrithiamine-induced thiamine deficiency (PTD), was used to investigate the dynamic role of hippocampal and striatal acetylcholine (ACh) efflux across acquisition of a nonmatching-to-position (NMTP) T-maze task. Changes in ACh efflux were measured in rats
Zhiwei Huang et al.
PLoS genetics, 8(11), e1003083-e1003083 (2012-12-05)
Chloroquine (CQ) and other quinoline-containing antimalarials are important drugs with many therapeutic benefits as well as adverse effects. However, the molecular targets underlying most such effects are largely unknown. By taking a novel functional genomics strategy, which employs a unique

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務