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Key Documents

K2755

Sigma-Aldrich

2-酮基-3-脱氧辛烷 铵盐

≥97%

同義詞:

3-脱氧辛酮糖酸, KDO

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About This Item

線性公式:
C8H14O8 · NH3
CAS號碼:
分子量::
255.22
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

≥97%

形狀

powder

儲存溫度

−20°C

SMILES 字串

N.OCC(O)C1OC(O)(CC(O)C1O)C(O)=O

InChI

1S/C8H14O8.H3N/c9-2-4(11)6-5(12)3(10)1-8(15,16-6)7(13)14;/h3-6,9-12,15H,1-2H2,(H,13,14);1H3

InChI 密鑰

UDJBBKGYARWWNJ-UHFFFAOYSA-N

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應用

  • KDO类似物的合成:研究3-脱氧-D-甘露-辛酮糖酸(KDO)类似物的合成,包括2-酮基-3-脱氧辛酮酸铵盐。这些类似物是CMP-KDO合成酶的潜在抑制剂,对于开发治疗细菌感染的新药十分重要,有助于加强对细菌脂多糖合成的了解(Luthman et al., 1987)。

生化/生理作用

KDO 是一种唾液酸,是细菌脂多糖的成分以及抗生素研发的可用靶标。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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BMC medical research methodology, 13, 127-127 (2013-10-24)
Previous reviews of cluster randomised trials have been critical of the quality of the trials reviewed, but none has explored determinants of the quality of these trials in a specific field over an extended period of time. Recent work suggests
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Francisella tularensis is a category-A select agent and is responsible for tularemia in humans and animals. The surface components of F. tularensis that contribute to virulence are not well characterized. An electron-dense capsule has been postulated to be present around
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PloS one, 7(4), e32359-e32359 (2012-04-13)
We previously reported that neuraminidase (NA) pretreatment of human PBMCs markedly increased their cytokine response to lipopolysaccharide (LPS). To study the mechanisms by which this occurs, we transfected HEK293T cells with plasmids encoding TLR4, CD14, and MD2 (three components of

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