D99234

亚磷酸二乙酯

98%

• 同義詞: Diethoxyphosphine oxide, Diethyl acid phosphite, Diethyl hydrogen phosphite, Diethyl phosphonate, Hydrogen diethyl phosphite
• 線性公式: (C₂H₅O)₂P(O)H
• CAS號碼: 762-04-9
• 分子量：: 138.10
• Beilstein: 605759
• EC號碼: 212-091-6
• MDL號碼: MFCD00044573
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24894335
• NACRES: NA.22

屬性

• 品質等級: 200
• 化驗: 98%
• 形狀: liquid
• 折射率: n20/D 1.407 (lit.)
• bp: 50-51 °C/2 mmHg (lit.)
• 密度: 1.072 g/mL at 25 °C (lit.)
• SMILES 字串: [H]P(=O)(OCC)OCC
• InChI: 1S/C4H11O3P/c1-3-6-8(5)7-4-2/h8H,3-4H2,1-2H3
• InChI 密鑰: MJUJXFBTEFXVKU-UHFFFAOYSA-N

描述

一般說明

Diethyl phosphite is the organophosphorus compound used as a phosphorylating agent in organic synthesis.

應用

Applications of diethyl phosphite (DEP):

• It can undergo condensation with aldehydes or ketones and an amine to form α-aminophosphonates under solvent-free and catalyst-free conditions.
• Reduction of gem-dibromo derivatives using diethyl phosphite in the presence of triethylamine gives monobromocyclopropanes.
• Along with 4-dimethylaminopyridine, it can be used as a ligand for nickel-catalyzed cross-coupling of aryl and heteroaryl bromides, chlorides or sulfonates with arylzinc reagents.
• It can be used for the catalytic asymmetric hydrophosphonylation of enones in the presence of a dinuclear zinc complex to form γ-oxo-phosphonates.
• DEP can undergo Michael addition to α,β-unsaturated malonates to form β-phosphonomalonates in the presence of recyclable nano γ-ferric oxide-pyridine based catalyst.

安全資訊

• 象形圖: GHS05,GHS07
• 訊號詞: Danger
• 危險聲明: H317,H318
• 防範說明: P261 - P272 - P280 - P302 + P352 - P305 + P351 + P338 - P333 + P313
• 危險分類: Eye Dam. 1 - Skin Sens. 1B
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 179.6 °F - closed cup
• 閃點（°C）: 82 °C - closed cup
• 個人防護裝備: Eyeshields, Gloves, type ABEK (EN14387) respirator filter