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Key Documents

ALD00544

Sigma-Aldrich

丝氨酸水解酶抑制剂20

≥95%

同義詞:

tert-Butyl methyl(2-(N-methyl-1H-pyrazole-1-carboxamido)ethyl)carbamate, SHI-20

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About This Item

經驗公式(希爾表示法):
C13H22N4O3
CAS號碼:
分子量::
282.34
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

≥95%

形狀

solid

SMILES 字串

CN(CCN(C(OC(C)(C)C)=O)C)C(N1N=CC=C1)=O

InChI

1S/C13H22N4O3/c1-13(2,3)20-12(19)16(5)10-9-15(4)11(18)17-8-6-7-14-17/h6-8H,9-10H2,1-5H3

InChI 密鑰

YEPRRJPGFVACBT-UHFFFAOYSA-N

應用

Serine hydrolase inhibitors are small molecule fragments that react in vitro with the serine hydrolase class of proteins. They are amenable to further modification to create novel inhibitors of this class of protein.

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Katerina Otrubova et al.
Bioorganic & medicinal chemistry letters, 24(16), 3807-3813 (2014-07-20)
Two libraries of modestly reactive ureas containing either electron-deficient acyl anilines or acyl pyrazoles were prepared and are reported as screening libraries for candidate serine hydrolase inhibitors. Within each library is a small but powerful subset of compounds that serve

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