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Merck
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重要文件

A77806

Sigma-Aldrich

4-氨基吡唑并[3,4-d]嘧啶

98%

同義詞:

1H-Pyrazolo[3,4-d]pyrimidine-4-ylamine, 4-Amino-1H-pyrazolo[3,4-d]pyrimidine

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About This Item

經驗公式(希爾表示法):
C5H5N5
CAS號碼:
分子量::
135.13
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
形狀:
powder
化驗:
98%

化驗

98%

形狀

powder

mp

>325 °C (lit.)

SMILES 字串

Nc1ncnc2[nH]ncc12

InChI

1S/C5H5N5/c6-4-3-1-9-10-5(3)8-2-7-4/h1-2H,(H3,6,7,8,9,10)

InChI 密鑰

LHCPRYRLDOSKHK-UHFFFAOYSA-N

應用

可显著降低大鼠体内的血清胆固醇。

象形圖

Skull and crossbones

訊號詞

Danger

危險分類

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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分析證明 (COA)

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S Azhar et al.
Biochemistry, 23(20), 4533-4538 (1984-09-25)
These studies were done to examine the effect of gonadotropin on rat luteal 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity (the rate-limiting step in cholesterol biosynthesis) in ovaries of pregnant mare's serum gonadotropin (PMSG)-human chorionic gonadotropin (hCG) primed rats. Administration
M Bertolotti et al.
Journal of lipid research, 37(8), 1812-1822 (1996-08-01)
This study was performed to investigate the effects of 17 alpha-ethinyl estradiol, a potent hypocholesterolemic agent at pharmacological doses, on cholesterol balance in the liver and extrahepatic tissues of the rat in vivo. Female Sprague-Dawley rats were treated with 17
R F Aten et al.
Endocrinology, 135(2), 533-539 (1994-08-01)
Reactive oxygen species, such as superoxide, hydrogen peroxide, and lipid peroxides, impair luteal function. Vitamin E, a lipophilic antioxidant vitamin, provides a major avenue of protection by scavenging free radicals and terminating lipid peroxidation. We previously showed that ovarian vitamin
S Wu-Pong et al.
The Journal of investigative dermatology, 102(5), 799-802 (1994-05-01)
Barrier perturbation stimulates epidermal cholesterol synthesis, which plays an important role in restoring barrier function. In the present study, we examined whether changes in serum cholesterol levels or nutrition regulate epidermal cholesterol synthesis in hairless mice. Serum cholesterol levels were
J F Goodrum
Journal of neurochemistry, 60(4), 1564-1566 (1993-04-01)
Following a nerve crush, cholesterol from degenerating myelin is retained within the nerve and reutilized for new myelin synthesis during nerve regeneration, apparently via a lipoprotein-mediated process. Because at least some serum components have access to the endoneurium of injured

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