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Merck
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Key Documents

937185

Sigma-Aldrich

Polysuccinimide

≥95%, average Mw 60000

同義詞:

PSI

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About This Item

線性公式:
(C4H3NO2)n
CAS號碼:
分類程式碼代碼:
12352142
NACRES:
NA.21

agency

suitable for controlled release

品質等級

化驗

≥95%

形狀

powder or chunks

分子量

average Mw 60000

顏色

white to light brown

應用

advanced drug delivery
agriculture
cosmetics

一般說明

Polysuccinimide (PSI), commonly synthesized through thermal polymerization, is a polyimide precursor for the production of such biocompatible and degradable polymers namely polyaspartic acid and various polyaspartamides. Polyaspartic acid is produced by hydrolysis of PSI under alkaline condition while polyaspartamide is produced by ring opening of PSI using a nucleophilic reagent. The presence of amide linkages in these polymers gives them peptide-like structures which is prone to hydrolysis and subsequent degradation. These derivatives could be potential substitutes for different polyamino acids in many medical applications.

應用

Polysuccinimide (PSI) has been used for a variety of applications including:
  • As a nanocarrier or microcarrier delivery vehicle in pharmaceutical, cosmetic, and agriculture (agrochemical) fields
  • As electrospun fibers, films, meshes or mats for wound healing applications
  • As nanofibers for electronic and biosensor applications
  • As a sustainable and environmentally friendly alternative to non-degradable polymers

特點和優勢

  • Biodegradable by hydrolysis allowing for sustained and controlled delivery
  • High swelling ratio with superabsorbent properties
  • Water soluble
  • Peptide-like and biocompatible

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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