934321

L-Valyl-L-citrulline

≥95%

• 同義詞: L-Valyl-N⁵-(aminocarbonyl)-L-ornithine, Val-Cit
• 經驗公式（希爾表示法）: C₁₁H₂₂N₄O₄
• CAS號碼: 159858-33-0
• 分子量：: 274.32
• 分類程式碼代碼: 12352209
• NACRES: NA.21

屬性

• 品質等級: 100
• 化驗: ≥95%
• 形狀: powder or crystals
• 顏色: off-white to light yellow
• 儲存溫度: 2-8°C

描述

應用

This is a cathepsin cleavable linker used in the construction of antibody drug conjugates (ADC & Bioconjugation).

特點和優勢

Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. The Boc group can be deprotected under acidic conditions to generate a free amine group. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable