934305

Pomalidomide-PEG1-C2-amine HCl

≥95.0%

• 同義詞: 4-[[2-(2-Aminoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
• 經驗公式（希爾表示法）: C₁₇H₂₀N₄O₅ · xHCl
• CAS號碼: 2154342-56-8
• 分子量：: 360.36 (free base basis)
• MDL號碼: MFCD32666562
• 分類程式碼代碼: 12352116
• NACRES: NA.21

屬性

• ligand: pomalidomide
• 品質等級: 100
• 化驗: ≥95.0%
• 形狀: powder or crystals
• 顏色: faint yellow to dark yellow
• 儲存溫度: 2-8°C
• SMILES 字串: Cl.O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCOCCN)C3C2=O)CC1
• InChI: 1S/C17H20N4O5.ClH/c18-6-8-26-9-7-19-11-3-1-2-10-14(11)17(25)21(16(10)24)12-4-5-13(22)20-15(12)23;/h1-3,12,19H,4-9,18H2,(H,20,22,23);1H
• InChI 密鑰: LQYLHZFKGOZTOH-UHFFFAOYSA-N

描述

應用

Technology Spotlight:

Degrader Building Blocks for Targeted Protein Degradation

Protein Degrader Building Blocks

其他說明

Targeted Protein Degradation by Small Molecules

Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERG

Small-Molecule PROTACS: New Approaches to Protein Degradation

Targeted Protein Degradation: from Chemical Biology to Drug Discovery

Impact of linker length on the activity of PROTACs

法律資訊

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

安全資訊

• 象形圖: GHS08
• 訊號詞: Danger
• 危險聲明: H360D
• 防範說明: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危險分類: Repr. 1B
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable