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Merck
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重要文件

928925

Sigma-Aldrich

Poly(ethylene glycol)-block-poly(2-(Dimethylamino)ethyl methacrylate)

quaternized, PEG average Mn 5,000, quaternized PDMAEMA Mn 18,000

同義詞:

PEG-PQDMAEMA, Quaternized PEG-PDMAEMA

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About This Item

線性公式:
CH3(C2H4O)nC6H7O2N(C9H18O2NCl)mC7H5S2
分類程式碼代碼:
51171641
NACRES:
NA.25

品質等級

形狀

powder

分子量

PEG average Mn 5,000

顏色

white to pink

一般說明

Poly(ethylene glycol)-block-Poly(2-(Dimethylamino)ethyl methacrylate) quaternized (PEG-b-PQDMAEMA) is a biocompatible block polyelectrolyte composed of a neutral PEG block and a cationic quaternized Poly(2-(Dimethylamino)ethyl methacrylate) (PDMAEMA) block. The PQDMAEMA carries quaternary ammonium salt moieties along the polymer chain.

應用

  • Antimicrobial applications
  • Non-viral gene delivery

    PEG-b-PQDMAEMA is a versatile polymer with applications in antimicrobial applications and gene delivery. Due to its high efficacy in antimicrobial systems, it is an ideal candidate for the fabrication of long-lasting, contact-active bactericidal materials. PQDMAEMA is also a promising material for non-viral gene delivery. PEGylation of PQDMAEMA reduces cytotoxicity and increases gene delivery efficiency.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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Quaternized poly(2-(dimethylamino)ethyl methacrylate)-grafted agarose copolymers for multipurpose antibacterial applications
Xu LQ, et al.
Royal Society of Chemistry Advances, 5, 61742-61742 (2015)

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