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Merck
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Key Documents

923753

Sigma-Aldrich

INVIVO-GEL TGF-β bioink

suitable for 3D bioprinting applications

同義詞:

3D bioprinting, 3DBP, ECM

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About This Item

分類程式碼代碼:
12162002
NACRES:
NA.23

品質等級

儲存溫度

2-8°C

應用

INVIVO-GEL TGF-β bioink is specifically developed and optimized for 3D bioprinting applications. The INVIVO-GEL TGF-β bioink kit includes optimally formulated TGF-mimetic peptide conjugated gelatin-based hydrogel complex packed in syringe for easy dispensing. The kit also includes Gel-linker, which reinforces mechanical stability. A transparent hydrogel forms when contents are properly mixed and exposed to UV light. This bioink is capable of generating mechanically stable 3D structures that can be maintained for days in the culture environment. TGF may promote ECM production, as reported by numerous studies demonstrating the dramatic increase in matrix synthesis and deposition by vascular smooth muscle and endothelial cells when grown on hydrogels with tethered TGF-β.

成分

INVIVO-GEL TGF-β in syringe 5mL x 2
Gel-linker(A) powder 500µL x 1
Gel-linker(B) powder 1µL x 1

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1


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Gelatin methacryloyl and its hydrogels with an exceptional degree of controllability and batch-to-batch consistency
Zhu et al.
Scientific Reports, 9, 6863-6863 (2019)
Designing Gelatin Methacryloyl (GelMA)-Based Bioinks for Visible Light Stereolithographic 3D Biofabrication
Kumar H et al.
Macromolecular Bioscience, 11 (2020)
Shining Xiao et al.
Stem cell reviews and reports, 15(5), 664-679 (2019-06-04)
Gelatin methacrylate (GelMA)-based hydrogels are gaining a great deal of attention as potentially implantable materials in tissue engineering applications because of their biofunctionality and mechanical tenability. Since different natural tissues respond differently to mechanical stresses, an ideal implanted material would
Kan Yue et al.
Biomaterials, 73, 254-271 (2015-09-29)
Gelatin methacryloyl (GelMA) hydrogels have been widely used for various biomedical applications due to their suitable biological properties and tunable physical characteristics. GelMA hydrogels closely resemble some essential properties of native extracellular matrix (ECM) due to the presence of cell-attaching
Mengxiang Zhu et al.
Scientific reports, 9(1), 6863-6863 (2019-05-06)
Gelatin methacryloyl (GelMA) is a versatile material for a wide range of bioapplications. There is an intense interest in developing effective chemical strategies to prepare GelMA with a high degree of batch-to-batch consistency and controllability in terms of methacryloyl functionalization

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