910015

17-Azido-3,6,9,12,15-pentaoxaheptadecanoic acid

≥95%

• 同義詞: Azido-PEG₅-CH₂CO₂H, Azido-PEG₅-acid, N₃-PEG₅-CH₂COOH
• 經驗公式（希爾表示法）: C₁₂H₂₃N₃O₇
• CAS號碼: 217180-81-9
• 分子量：: 321.33
• MDL號碼: MFCD31561141
• 分類程式碼代碼: 12352106

屬性

• 化驗: ≥95%
• 形狀: (Liquid or Semi-solid or Paste or Solid)
• 反應適用性: reaction type: click chemistry; reagent type: cross-linking reagent
• 官能基: azide; carboxylic acid
• 儲存溫度: 2-8°C
• SMILES 字串: OC(COCCOCCOCCOCCOCCN=[N+]=[N-])=O

描述

應用

This heterobifunctional, PEGylated crosslinker 17-Azido-3,6,9,12,15-pentaoxaheptadecanoic acid features a carboxyl group at one end and azide at the other. The hydrophillic PEG linker facilitates solubility in biological applications. This azido-PEG₅-acid linker can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^® molecules) for targeted protein degradation.

其他說明

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

法律資訊

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable