902527

Amino-PEG5-t-butyl ester

≥95%

• 同義詞: tert-Butyl-1-amino-3,6,9,12,15-pentaoxaoctadecan-18-oate, H₂N-PEG₅-CH₂CH₂COOtBu
• 經驗公式（希爾表示法）: C₁₇H₃₅NO₇
• CAS號碼: 1446282-18-3
• 分子量：: 365.46
• MDL號碼: MFCD25424125
• 分類程式碼代碼: 51171641

屬性

• 化驗: ≥95%
• 形狀: liquid
• 反應適用性: reagent type: cross-linking reagent
• 折射率: n/D 1.4534
• 密度: 1.4690 g/mL
• 官能基: amine; ester
• 儲存溫度: −20°C
• SMILES 字串: NCCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O

描述

應用

This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Amino-PEG5-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^® molecules) for targeted protein degradation.

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法律資訊

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°C）: No data available