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Merck
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重要文件

905534

Sigma-Aldrich

(2-(Phenoxycarbonyl)phenyl)boronic acid

greener alternative

≥95%

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About This Item

經驗公式(希爾表示法):
C13H11BO4
CAS號碼:
分子量::
242.04
MDL號碼:
分類程式碼代碼:
12352106

化驗

≥95%

形狀

powder or crystals

反應適用性

reagent type: catalyst

環保替代產品特色

Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

150-152 °C

環保替代類別

儲存溫度

2-8°C

一般說明

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應用

(2-(Phenoxycarbonyl)phenyl)boronic acid is a boronic acid catalyst from the Hall Group developed for chemoselective activation of oxime N−OH bonds for the preparation of functionalized amide compounds via Beckmann Rearrangement. This catalyst is efficient to transform various diaryl, aryl-alkyl, heteroaryl-alkyl, and dialkyl oximes to amide products under ambient conditions.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Xiaobin Mo et al.
Journal of the American Chemical Society, 140(15), 5264-5271 (2018-03-23)
Catalytic activation of hydroxyl functionalities is of great interest for the production of pharmaceuticals and commodity chemicals. Here, 2-alkoxycarbonyl- and 2-phenoxycarbonyl-phenylboronic acid were identified as efficient catalysts for the direct and chemoselective activation of oxime N-OH bonds in the Beckmann
Scope and Mechanism of a True Organocatalytic Beckmann Rearrangement with a Boronic Acid/Perfluoropinacol System under Ambient Conditions.
Mo X, et al.
Journal of the American Chemical Society, 140(15), 5264-5271 (2018)

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