905186

(9-Bromononyl)triphenylphosphonium bromide

• 同義詞: Bromononane TPP mitochondrial tag, Mitochondria-targeting probe building block, Phosphonium lipocation tag
• 經驗公式（希爾表示法）: C₂₇H₃₃Br₂P
• CAS號碼: 90052-38-3
• 分子量：: 548.33
• 分類程式碼代碼: 12352200

屬性

• 形狀: liquid
• 儲存溫度: 2-8°C
• InChI: 1S/C27H33BrP.BrH/c28-23-15-4-2-1-3-5-16-24-29(25-17-9-6-10-18-25,26-19-11-7-12-20-26)27-21-13-8-14-22-27;/h6-14,17-22H,1-5,15-16,23-24H2;1H/q+1;/p-1
• InChI 密鑰: ACKJFSDDEOFXHT-UHFFFAOYSA-M

描述

應用

Mitochondria perform several functions in the cell, and dysfunction has been implicated in various organ systems and disease states, including neurodegenerative disorders and cancers. The targeting of small molecules to the mitochondria can help to probe and better understand this relationship. This bromononane triphenylphosphine (TPP) tag is conjugated to small molecules to localize them to the mitochondria in cells where the TPP cations facilitate both cellular uptake and accumulation in the mitochondria.

其他說明

Conjugates of 2,4-Dihydroxybenzoate and Salicylhydroxamate and Lipocations Display Potent Antiparasite Effects by Efficiently Targeting the Trypanosoma brucei and Trypanosoma congolense Mitochondrion

Targeting lipophilic cations to mitochondria

Photoswitchable polyfluorophores based on perylenemonoimide-dithienylethene conjugates as super-resolution MitoTrackers

安全資訊

• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable