79522

P,P-二甲基膦酰乙酸叔丁酯

≥97.0% (GC)

• 同義詞: (叔丁氧羰基)甲基膦酸二甲酯
• 線性公式: (CH₃O)₂P(O)CH₂COOC(CH₃)₃
• CAS號碼: 62327-21-3
• 分子量：: 224.19
• Beilstein: 4861886
• MDL號碼: MFCD00042939
• 分類程式碼代碼: 12352108
• PubChem物質ID: 57652799
• NACRES: NA.22

屬性

• 品質等級: 100
• 化驗: ≥97.0% (GC)
• 形狀: liquid
• 反應適用性: reaction type: C-C Bond Formation
• 折射率: n20/D 1.434
• bp: 86-87 °C/0.02 mmHg (lit.)
• 密度: 1.131 g/mL at 20 °C (lit.)
• 官能基: ester; phosphonate
• SMILES 字串: COP(=O)(CC(=O)OC(C)(C)C)OC
• InChI: 1S/C8H17O5P/c1-8(2,3)13-7(9)6-14(10,11-4)12-5/h6H2,1-5H3
• InChI 密鑰: SAZYDWOWLRDDRQ-UHFFFAOYSA-N

描述

應用

Reactant for:

• Preparation of phosphonate terminated PPH dendrimers as anti-HIV-1 agents
• Preparation of monodehydro diketopiperazines from ketoacyl amino acid amides via acid-catalyzed cyclization
• Preparation of α,β-unsaturated esters for use in the guanidine-catalyzed oxa-Michael addition
• Preparation of myxopyronin B and desmethyl myxopyronin B analogs, with antibacterial activity and inhibitory activity against bacterial RNA polymerase
• Allylation and subsequent ring-closing metathesis in presence of Grubbs′ catalyst or intramolecular rhodium-catalyzed cyclopropanation reactions

其他說明

Horner-Wittig 试剂，优先生成 (E)-α,β-不饱和酯，这种酯可与酸发生轻度皂化反应。也可用于通过还原烷基化反应合成衍生物

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 230.0 °F - closed cup
• 閃點（°C）: 110.0 °C - closed cup
• 個人防護裝備: Eyeshields, Gloves, type ABEK (EN14387) respirator filter