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Merck
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重要文件

773409

Sigma-Aldrich

Poly(L-lactide), 2-bromoisobutyryl terminated

average Mn 10,000, PDI ≤1.1

同義詞:

10 k PLLA-ATRP, ATRP Macromonomer, ATRP terminated PLLA, PLA

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About This Item

線性公式:
H(C3H4O2)nC6H10BrO3
分類程式碼代碼:
12162002
NACRES:
NA.23

形狀

solid

光學活性

[α]22/D -145°, c = 0.1% in chloroform

分子量

average Mn 10,000

mp

160-165 °C

蛋白質二硫鍵異構酶

≤1.1

儲存溫度

2-8°C

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應用

Macroinitiator for atom transfer radical polymerization (ATRP) to prepare block copolymers. Poly(L-lactide) is commonly used in drug delivery.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Oh; Jung Kwon.
Soft Matter, 7, 5096-5096 (2011)

文章

Microparticle drug delivery systems have been extensively researched and applied to a wide variety of pharmaceutical and medical applications due to a number of advantages including injectability, local applicability to target tissues and sites, and controlled drug delivery over a given time period.

Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.

Wide range of functional polymers for biomedical applications have been synthesized and structurally characterized. Several classes of polymers including biodegradable polymers, hydrophilic & amphiphilic polymers, and stimuli responsive polymers have been prepared using controlled and directed functionalization via "living" polymerization such as RAFT, ionic and ring opening polymerization. Selected polymers have been studied for their structure-properties relationship. "

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