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729159

Sigma-Aldrich

聚乙二醇甲醚巯基

average MN 6,000, chemical modification reagent thiol reactive, methoxy, thiol

同義詞:

PEG 硫醇, mPEG 硫醇, 甲氧基 PEG 硫醇, 甲氧基聚乙二醇硫醇

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About This Item

線性公式:
CH3O(CH2CH2O)nCH2CH2SH
分類程式碼代碼:
12162002
NACRES:
NA.23

product name

聚乙二醇甲醚巯基, average Mn 6,000

形狀

solid

品質等級

100

分子量

average Mn 6,000

反應適用性

reagent type: chemical modification reagent
reactivity: thiol reactive

mp

56-61 °C

Mw/Mn

≤1.2

Ω-end

thiol

α-end

methoxy

聚合物結構

shape: linear
functionality: monofunctional

運輸包裝

dry ice

儲存溫度

−20°C

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相關類別

一般說明

聚乙二醇单甲醚硫醇（mPEG硫醇）是一种thiol) 是一种硫醇封端的生物相容性聚合物，广泛应用于金纳米颗粒的表面功能化。硫醇结构单元通过共价硫醇盐–金属键形成自组装单层（SAM），从而以高亲和力与金表面结合。mPEG硫醇包裹的金纳米颗粒可用于生物传感器和药物递送系统等领域。

應用

聚乙二醇单甲醚硫醇包裹的 金纳米颗粒可用于通过光学方法测定 三聚氰胺。 它也可用于制造油水分离用可开关超润湿膜。

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H315,H319,H335

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析證明 (COA)

Lot/Batch Number
MKCL4582
MKCH0719
MKCF5112
MKBW7623V
MKBS3186V

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Amina Ghorbel et al.
Bioelectrochemistry (Amsterdam, Netherlands), 137, 107642-107642 (2020-09-28)
The use of conductive nanoparticles (NPs) was previously proposed as a way to locally amplify the electric field (EF) intensity at the cell membrane to enhance cell electroporation. To achieve this, a close distance between the NPs and the cell
Jairo Pinto Oliveira et al.
Scientific reports, 9(1), 13859-13859 (2019-09-27)
Antibody-coated nanoparticles have recently attracted considerable attention, with the focus falling on diagnostics. Nevertheless, controlled antibody bioconjugation remains a challenge. Here, we present two strategies of bioconjugation with the aim of evaluating the best approach for the coupling of antibodies

文章

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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