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717142

Sigma-Aldrich

聚乙二醇（PEG）二硫

average Mn 1,000, thiol

同義詞:

聚乙二醇二硫醇

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About This Item

線性公式:
HSCH2CH2(OCH2CH2)nSH
分類程式碼代碼:
12162002
NACRES:
NA.23

product name

聚乙二醇（PEG）二硫, average Mn 1,000

形狀

solid

分子量

average Mn 1,000

反應適用性

reagent type: cross-linking reagent
reactivity: thiol reactive

mp

29-33 °C

Ω-end

thiol

α-end

thiol

聚合物結構

shape: linear
functionality: homobifunctional

儲存溫度

2-8°C

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相關類別

應用

硫醇官能化的纳米颗粒可用于粘膜粘附药物递送，合成二硫醇封端的两亲性二嵌段共聚物，双配位基二硫醇-聚（乙二醇）-聚（d,l-丙交酯）（SH2-PEG-PDLLA）。通过简单的配体交换，金纳米颗粒可以很容易地用PEG二硫醇官能化。

其他說明

分子量：Mn为900-1,100

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H315,H319,H335

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析證明 (COA)

Lot/Batch Number
MKCQ0755
MKCH8048
MKCG7818
MKBV8994V
MKBV8605V

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Nadeau J
Introduction to Experimental Biophysics: Biological Methods for Physical Scientists null
Jian Yang et al.
Biomacromolecules, 15(4), 1346-1354 (2014-03-13)
Thiol-modified nanoparticles have potential applications in mucoadhesive drug delivery and have been examined in this regard for topical ocular delivery. In this paper we provide a simple method for the synthesis of a dithiol terminated amphiphilic diblock copolymer. Bidentate dithiol-poly(ethylene

文章

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The use of hydrogel-based biomaterials for the delivery and recruitment of cells to promote tissue regeneration in the body is of growing interest. This article discussed the application of hydrogels in cell delivery and tissue regeneration.

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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