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Merck
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重要文件

646598

Sigma-Aldrich

环丁基硼酸

≥95.0%

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About This Item

經驗公式(希爾表示法):
C4H9BO2
CAS號碼:
分子量::
99.92
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

≥95.0%

形狀

solid

mp

118-123 °C (lit.)

儲存溫度

2-8°C

SMILES 字串

OB(O)C1CCC1

InChI

1S/C4H9BO2/c6-5(7)4-2-1-3-4/h4,6-7H,1-3H2

InChI 密鑰

MIUALDDWOKMYDA-UHFFFAOYSA-N

應用

  • Reagent used in palladium-catalyzed arylation and alkylation of diphenylisoxazole with boronic acids via C-H activated isoxazole palladacycle intermediate

  • Reagent used in the preparation of cyclobutyl arenes and heteroarenes via palladium catalyzed Suzuki-Miyaura cross-coupling reaction of potassium cyclobutyltrifluoroborate intermediate with aryl and heteroaryl chlorides

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

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Palladium-Catalyzed Arylation and Alkylation of 3,5-Diphenylisoxazole with Boronic Acids via C-H Activation
J. Chu, et al.,
Organometallics, 27, 5173-5176 (2008)
Gary A Molander et al.
The Journal of organic chemistry, 73(19), 7481-7485 (2008-09-02)
Suitable conditions were found for the Suzuki-Miyaura cross-coupling reaction of potassium cyclopropyl- and cyclobutyltrifluoroborates with aryl chlorides. Both of these secondary alkyl trifluoroborates coupled in moderate to excellent yield with electron-rich, electron-poor, and hindered aryl chlorides to give a variety

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