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重要文件

540250

Sigma-Aldrich

(S)-(+)-1,2-丙二醇

96%

同義詞:

(S)-(+)-丙二醇

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About This Item

線性公式:
CH3CH(OH)CH2OH
CAS號碼:
分子量::
76.09
Beilstein:
1718871
MDL號碼:
分類程式碼代碼:
12352001
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

96%

光學活性

[α]20/D +16.5°, neat

光學純度

ee: 98% (GLC)

折射率

n20/D 1.432 (lit.)

bp

186-188 °C/765 mmHg (lit.)

密度

1.036 g/mL at 20 °C (lit.)

官能基

hydroxyl

SMILES 字串

C[C@H](O)CO

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3/t3-/m0/s1

InChI 密鑰

DNIAPMSPPWPWGF-VKHMYHEASA-N

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應用

S)-(+)-1,2-丙二醇可用作合成以下物质的反应物:
  • 在二甲基氨基吡啶(DMAP)催化剂存在的情况下以介晶羧酸通过酯化反应制备的光活性手性( S)-1, 2-丙二醇衍生物。
  • 通过Mitsunobu 反应制备的3,4-乙烯二氧噻吩。
  • 在高碘酸钠和氯化钌催化剂存在的情况下制备的邻二醇环硫酸酯。

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

217.4 °F - closed cup

閃點(°C)

103 °C - closed cup


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分析證明 (COA)

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A A Melo et al.
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To determine whether the administration of mitomycin C prevents propylene glycol exposure from inducing middle-ear cholesteatoma and otitis media, in a rat model. Twenty-four Wistar rats underwent intratympanic injections on days 1, 8 and 15, via the tympanic membrane pars
H Fromme et al.
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Diclofenac-loaded phospholipid vesicles, namely conventional liposomes, ethosomes and PEVs (penetration enhancer-containing vesicles) were developed and their efficacy in TPA (phorbol ester) induced skin inflammation was examined. Vesicles were made from a cheap and unpurified mixture of phospholipids and diclofenac sodium;
Kenneth B Sloan et al.
Journal of cosmetic science, 64(3), 181-192 (2013-06-12)
It would be useful to develop a surrogate for animal skin, which could be use to predict flux through human skin. The fluxes (and physicochemical properties) of sunscreens and other compounds from propylene glycol (PG):water (AQ), 30:70, through human skin

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