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Merck
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Key Documents

523690

Sigma-Aldrich

3-氨基-1-金刚烷醇

96%

同義詞:

1-氨基-3-羟丙醇金刚烷, 1-氨基-3-金刚烷, 3-氨基-1-羟丙醇金刚烷, 3-氨基三环[3,3,1,1(3,7)]癸烷-1-醇, (3-羟基金刚烷-1-基)胺

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About This Item

經驗公式(希爾表示法):
C10H17NO
CAS號碼:
分子量::
167.25
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

96%

形狀

solid

mp

265 °C (dec.) (lit.)

SMILES 字串

N[C@]12C[C@@H]3C[C@H](C1)C[C@@](O)(C3)C2

InChI

1S/C10H17NO/c11-9-2-7-1-8(3-9)5-10(12,4-7)6-9/h7-8,12H,1-6,11H2/t7-,8+,9+,10-

InChI 密鑰

DWPIPTNBOVJYAD-FIRGSJFUSA-N

應用

用于合成具有抗高血糖特性的抑制剂。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

230.0 °F - closed cup

閃點(°C)

110 °C - closed cup

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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NOVEL TRICYCLIC CYANOPYRROLIDINE DERIVATIVES AS DPP4 INHIBITORS: AN IMPROVED SYNTHESIS OF TRICYCLIC a-CYCNOPYRROLIDINE FROM CAMPHOR.
Arumugam K and Anitha M.
Rasayan Journal of Chemistry, 6(3), 230-237 (2013)
Nieves Fresno et al.
PloS one, 9(12), e113841-e113841 (2014-12-02)
Paracetamol also known as acetaminophen, is a widely used analgesic and antipyretic agent. We report the synthesis and biological evaluation of adamantyl analogues of paracetamol with important analgesic properties. The mechanism of nociception of compound 6a/b, an analog of paracetamol
A Facile and Economical Method to Synthesize Vildagliptin.
Deng Y, et al.
Letters in Organic Chemistry, 11(10), 780-784 (2014)
Edwin B Villhauer et al.
Journal of medicinal chemistry, 46(13), 2774-2789 (2003-06-13)
Dipeptidyl peptidase IV (DPP-IV) inhibition has the potential to become a valuable therapy for type 2 diabetes. The synthesis and structure-activity relationship of a new DPP-IV inhibitor class, N-substituted-glycyl-2-cyanopyrrolidines, are described as well as the path that led from clinical
Ramzia I El-Bagary et al.
International journal of biomedical science : IJBS, 7(3), 201-208 (2011-09-01)
Two reversed-phase liquid chromatographic (RP-LC) methods are described for the determination of two binary mixtures of hypoglycemic agents. In the first method, vildagliptin (VDG) was determined in the presence of 3-amino-1-adamantanol (AAD), a synthetic intermediate and impurity of VDG. In

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