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Merck
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479306

Sigma-Aldrich

顺二氯化二胺（II）

≥99.9% trace metals basis

同義詞:

顺铂, 顺-二氯二氨基铂(II), 顺式-二胺二氯铂, 顺氯氨铂

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About This Item

線性公式:
Pt(NH3)2Cl2
CAS號碼:
15663-27-1
分子量：:
300.05
EC號碼:
239-733-8
MDL號碼:
MFCD00011623
分類程式碼代碼:
12161600
PubChem物質ID:
24871609
NACRES:
NA.22

品質等級

100

化驗

≥99.9% trace metals basis

反應適用性

core: platinum
reagent type: catalyst

mp

270 °C (lit.)

抗生素活性譜

neoplastics

作用方式

DNA synthesis | interferes

SMILES 字串

N.N.Cl[Pt]Cl

InChI

1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2

InChI 密鑰

LXZZYRPGZAFOLE-UHFFFAOYSA-L

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相關類別

應用

顺二氯化二胺（II）可用作模型药物以测试药物递送中各种药物载体的效率。
高活性化疗剂，可用于预防睾丸癌的进展。

生化／生理作用

强效的铂基抗肿瘤剂。与 DNA 二核苷酸 d(pGpG) 形成细胞毒性加合物，诱导链内交联。

象形圖

Skull and crossbonesHealth hazard
GHS06,GHS08

訊號詞

Danger

危險分類

Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

分析證明 (COA)

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