470791

2,6-二氟苯硼酸

98%

• 線性公式: F₂C₆H₃B(OH)₂
• CAS號碼: 162101-25-9
• 分子量：: 157.91
• MDL號碼: MFCD00792436
• 分類程式碼代碼: 12352103
• PubChem物質ID: 24870682
• NACRES: NA.22

屬性

• 品質等級: 100
• 化驗: 98%
• mp: 147-149 °C (lit.)
• 官能基: fluoro
• SMILES 字串: OB(O)c1c(F)cccc1F
• InChI: 1S/C6H5BF2O2/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3,10-11H
• InChI 密鑰: DBZAICSEFBVFHL-UHFFFAOYSA-N

描述

應用

2,6-Difluorophenylboronic acid can be used:

• As a substrate in the model reaction of Suzuki–Miyaura coupling with 4-chloro-3-methylanisole.
• To prepare 4-bromo-2,3′,5′,6-tetrafluorobiphenyl, a key intermediate for the synthesis of 2,6-difluorinated oligophenyls applicable in organic semiconductors.
• To prepare ethyl 4-(2,6-difluorophenyl)nicotinate, a key intermediate for the synthesis of 4-phenyl pyridine based potent TGR5 agonists.

其他說明

含有不定量的酸酐

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves