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Merck
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463442

Sigma-Aldrich

4-[2-(5-氯-2-甲氧基苯甲酰氨基)乙基]苯磺酰胺

95%

同義詞:

4-[2-(5-Chloro-2-methoxybenzamido)ethyl]phenylsulfonamide

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About This Item

線性公式:
ClC6H3(OCH3)CONHCH2C6H4SO2NH2
CAS號碼:
16673-34-0
分子量：:
368.84
EC號碼:
240-722-5
MDL號碼:
MFCD00193756
分類程式碼代碼:
12352100
PubChem物質ID:
24870067
NACRES:
NA.22

品質等級

100

化驗

95%

mp

209-214 °C (lit.)

SMILES 字串

COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(N)(=O)=O

InChI

1S/C16H17ClN2O4S/c1-23-15-7-4-12(17)10-14(15)16(20)19-9-8-11-2-5-13(6-3-11)24(18,21)22/h2-7,10H,8-9H2,1H3,(H,19,20)(H2,18,21,22)

InChI 密鑰

KVWWTCSJLGHLRM-UHFFFAOYSA-N

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相關類別

一般說明

5-Chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide is an organic building block. It has been reported as an intermediate in the synthesis of glyburide. Synthesis of 5-chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide has been reported.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

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Carlo Marchetti et al.
Journal of cardiovascular pharmacology, 63(4), 316-322 (2013-12-18)
The formation of the NLRP3 inflammasome in the heart during acute myocardial infarction amplifies the inflammatory response and mediates further damage. Glyburide has NLRP3 inhibitory activity in vitro but requires very high doses in vivo, associated with hypoglycemia. The aim
Reply to Letter Regarding Article," NLRP3 Inflammasome as a Therapeutic Target in Myocardial Infarction.
Takahashi M.
International Heart Journal, 55(4), 380-380 (2014)
Molecular regulation of cell fate in cerebral ischemia: role of the inflammasome and connected pathways
Trendelenburg G.
Journal of Cerebral Blood Flow and Metabolism (2014)

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