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Key Documents

283746

Sigma-Aldrich

4-(氨甲基)苯甲酸

97%, for peptide synthesis

同義詞:

PAMBA

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About This Item

線性公式:
H2NCH2C6H4CO2H
CAS號碼:
分子量::
151.16
Beilstein:
1100606
EC號碼:
MDL號碼:
分類程式碼代碼:
12352106
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.22

product name

4-(氨甲基)苯甲酸, 97%

品質等級

化驗

97%

形狀

powder

反應適用性

reaction type: solution phase peptide synthesis

mp

≥300 °C (lit.)

應用

peptide synthesis

SMILES 字串

NCc1ccc(cc1)C(O)=O

InChI

1S/C8H9NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,5,9H2,(H,10,11)

InChI 密鑰

QCTBMLYLENLHLA-UHFFFAOYSA-N

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應用

4-(氨基甲基)苯甲酸(PAMBA)可用于合成:
  • 钴羧酸膦酸酯。
  • Apoptozole(Az),具有促进突变囊性纤维化跨膜传导调节因子(CFTR)氯通道活性的膜运输的细胞效力。
  • 环肽,由 L-谷氨酸和 3-氨基苯甲酸组成,可用作各种阳离子和阴离子的受体。
  • 生物活性肽,具有有效的 GPR54(G 蛋白偶联受体)激动活性。

其他說明

4-(氨基甲基)苯甲酸也是一种抗出血剂,用于治疗内出血。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

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Sandra Osburn et al.
Rapid communications in mass spectrometry : RCM, 21(21), 3409-3419 (2007-09-29)
Formation of [bn+17+cat]+ is a prominent collision-induced dissociation (CID) pathway for Li+- and Na+-cationized peptides. Dissociation of protonated and Ag+-cationized peptides instead favors formation of the rival bn+/[bn-1+cat]+ species. In this study the influence of a 4-aminomethylbenzoic acid (4AMBz) residue
E M Gorskaia et al.
Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (1)(1), 87-90 (1995-01-01)
The possibility of the correction of intestinal microflora disorders and the functional activity of macrophages in dysbiosis, caused by the intragastric administration of ampiox, with the use of amben (PAMBA), an inhibitor of proteolytic enzymes, was studied. Quantitative and qualitative
Carlos F R A C Lima et al.
The journal of physical chemistry. A, 111(42), 10598-10603 (2007-10-05)
The standard (p0 = 0.1 MPa) molar enthalpies of combustion of six aminomethylbenzoic acids were measured at T = 298.15 K by static bomb calorimetry. With these values, the standard molar enthalpies of formation in the crystalline state were obtained.
M N Iakushenko et al.
Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (1)(1), 77-79 (1998-04-09)
The examination of 49 newborn infants revealed that at the early neonatal period the character of the microbial colonization of the intestine depended on the kind of perinatal pathology: in lesions of the central nervous system and conjugation jaundice the
G A Chalyĭ et al.
Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (1)(1), 62-65 (1993-01-01)
The influence of protease-inhibiting preparations on the development of humoral immune response in diseases involving the development of secondary immunodeficiency (experimentally induced acute pancreatitis and staphylococcal infection) has been studied. Five injections of contrycal and epsilon-aminocaproic acid (epsilon-ACA), starting from

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