460516

(R)-(+)-4-氯-3-羟基丁酸乙酯

96%

• 線性公式: ClCH₂CH(OH)CH₂CO₂C₂H₅
• CAS號碼: 90866-33-4
• 分子量：: 166.60
• MDL號碼: MFCD00211242
• 分類程式碼代碼: 12352101
• PubChem物質ID: 24869705
• NACRES: NA.22

屬性

• 品質等級: 100
• 化驗: 96%
• 光學活性: [α]23/D +14°, neat
• 光學純度: ee: 97% (GLC)
• 折射率: n20/D 1.453 (lit.)
• bp: 93-95 °C/5 mmHg (lit.)
• 密度: 1.19 g/mL at 25 °C (lit.)
• 官能基: chloro; ester; hydroxyl
• SMILES 字串: CCOC(=O)C[C@@H](O)CCl
• InChI: 1S/C6H11ClO3/c1-2-10-6(9)3-5(8)4-7/h5,8H,2-4H2,1H3/t5-/m1/s1
• InChI 密鑰: ZAJNMXDBJKCCAT-RXMQYKEDSA-N

描述

應用

Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate is a chiral building block that can be used:

• To prepare allyl stannane, a precursor for the total synthesis of macrolide iriomoteolide-1b.
• As a starting material for the synthesis of a chiral g-αmino acid fragment, which in turn is used to prepare the immunosuppressive agent FR252921.

安全資訊

• 象形圖: GHS05
• 訊號詞: Danger
• 危險聲明: H318
• 防範說明: P280 - P305 + P351 + P338
• 危險分類: Eye Dam. 1
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 235.4 °F - closed cup
• 閃點（°C）: 113 °C - closed cup
• 個人防護裝備: Eyeshields, Gloves, type ABEK (EN14387) respirator filter