推薦產品
品質等級
化驗
95%
形狀
solid
bp
113 °C/10 mmHg (lit.)
mp
45-50 °C (lit.)
官能基
amine
chloro
SMILES 字串
CCN(CC)C(Cl)=S
InChI
1S/C5H10ClNS/c1-3-7(4-2)5(6)8/h3-4H2,1-2H3
InChI 密鑰
HUUSTUALCPTCGJ-UHFFFAOYSA-N
一般說明
Diethylthiocarbamoyl chloride is a thiocarbamoyl derivative. It has been reported to participate in the thionation of amides as thionating reagent.
應用
Diethylthiocarbamoyl chloride (N,N′-Diethylthiocarbamoyl chloride) may be used in the following syntheses:
- aryl isothiocyanates
- 5-substituted 4-methyl-2-thiazolyl diethyldithiocarbamates
- novel type of vasorelaxant hybrid compounds
Diethylthiocarbamoyl chloride may be used in the synthesis of 2,6-dimethyl-3,5-dicarbomethoxy-4-(2-difluoromethoxy- 5-isothiocyanatophenyl)-1,4-dihydropyridine.
訊號詞
Danger
危險聲明
危險分類
Skin Corr. 1B
儲存類別代碼
8A - Combustible corrosive hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
235.4 °F - closed cup
閃點（°C）
113 °C - closed cup
個人防護裝備
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Sulfated tungstate: An efficient catalyst for synthesis of thioamides via Kindler reaction.
Pathare SP, et al.
Applied Catalysis A: General, 425, 125-129 (2012)
L M Yagupolskii et al.
Journal of medicinal chemistry, 42(25), 5266-5271 (1999-12-22)
The synthesis and pharmacological properties of a novel type of vasorelaxant hybrid compounds are described. The investigated compounds originate from fluorinated 4-aryl-1,4-dihydropyridines, which are known calcium channel blockers, and/or from fluorinated analogues of pinacidil, which is an opener of ATP-sensitive
The Reaction of Arylamines with Diethylthiocarbamoyl Chloride. A New Synthesis of Aryl Isothiocyanates.
Sayigh AAR, et al.
The Journal of Organic Chemistry, 30(7), 2465-2466 (1965)
Derivatives of thiazolethiols.
D'Amico JJ, et al.
Journal of the American Chemical Society, 79(19), 5270-5276 (1957)
K R Frazier et al.
Journal of applied microbiology, 126(1), 79-86 (2018-08-31)
Disulfiram (Antabuse™) and its metabolites formed in vivo were evaluated as antibacterial agents against thirty species of Gram-positive and Gram-negative bacteria. The synergistic potential of disulfiram (DSF) and metabolite diethyldithiocarbamate (DDTC) with approved antibiotics were also compared by isobologram (checkerboard) analysis.
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