推薦產品
化驗
97%
形狀
powder
mp
173-175 °C (lit.)
SMILES 字串
Oc1ccccc1\N=N\c2ccccc2O
InChI
1S/C12H10N2O2/c15-11-7-3-1-5-9(11)13-14-10-6-2-4-8-12(10)16/h1-8,15-16H/b14-13+
InChI 密鑰
JFEVWPNAOCPRHQ-BUHFOSPRSA-N
一般說明
2,2′-Dihydroxyazobenzene is a small molecule inhibitor of ADP ribosyl cyclase and it attenuates angiotensin (Ang) II-induced hypertrophic responses. 2,2′-Dihydroxyazobenzene is formed during the oxidation of diclofenac by myeloperoxidase/hydrogen peroxide.
應用
2,2′-Dihydroxyazobenzene was used as complexing reagent in determination of aluminum in human serum by ion-pair reversed-phase partition HPLC.
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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E Kaneko et al.
Analytical chemistry, 63(20), 2219-2222 (1991-10-15)
An ion-pair reversed-phase partition high-performance liquid chromatography-spectrophotometric method is described for the determination of aluminum in human serum, based on its complexation with 2,2'-dihydroxyazobenzene. The chelate is separated on C18-bonded silica packing by using an aqueous methanol mobile phase containing
G Miyamoto et al.
Chemical research in toxicology, 10(4), 414-419 (1997-04-01)
Diclofenac is associated with a low, but significant, incidence of hepatotoxicity and bone marrow toxicity. It has been suggested that this could be due to a reactive acyl glucuronide. An alternative hypothesis is that an oxidative reactive metabolite could be
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Rukhsana Gul et al.
Cardiovascular research, 81(3), 582-591 (2008-08-23)
Here, we report the discovery of a small molecule inhibitor, 2,2'-dihydroxyazobenzene (DAB), of ADP ribosyl cyclase (ADPR-cyclase) and showed that this inhibitor attenuated angiotensin (Ang) II-induced hypertrophic responses. and results The intracellular concentration of free Ca(2+) [Ca(2+)](i) in adult rat
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