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Merck
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重要文件

217077

Sigma-Aldrich

6-羟基-1,3-苯唑硫醇-2-酮

≥98%

同義詞:

噻克索酮

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About This Item

經驗公式(希爾表示法):
C7H4O3S
CAS號碼:
分子量::
168.17
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

≥98%

mp

158-160 °C (lit.)

溶解度

95% ethanol: soluble 50 mg/mL, clear to very slightly hazy, colorless to yellow
benzene: soluble
diethyl ether: soluble
isopropanol: soluble
propylene glycol: soluble
toluene: soluble
water: insoluble

SMILES 字串

Oc1ccc2SC(=O)Oc2c1

InChI

1S/C7H4O3S/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3,8H

InChI 密鑰

SLYPOVJCSQHITR-UHFFFAOYSA-N

一般說明

Antimicrobial and cytostatic properties of 6-hydroxy-1,3-benzoxathiol-2-one has been investigated. Supramolecular structure of 6-hydroxy-1,3-benzoxathiol-2-one has been studied.

應用

6-Hydroxy-1,3-benzoxathiol-2-one was used in the synthesis of heterocycle-phosphor esters having potential antimicrobial activity.

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

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Contact dermatitis to thioxolone.
H Näher et al.
Contact dermatitis, 17(4), 250-251 (1987-10-01)
Keith Miller et al.
The Journal of antimicrobial chemotherapy, 65(12), 2566-2573 (2010-09-24)
We sought to identify and characterize new inhibitors of MurA and MurZ, which are enzymes involved in the early stages of bacterial peptidoglycan synthesis. A library of ∼650 000 compounds was screened for inhibitors of Escherichia coli MurA in an endpoint
Facile regioselective synthesis and antimicrobial activity of heterocycle-phosphor esters.
Abdou WM, et al.
Monatshefte fur Chemie / Chemical Monthly, 145(4), 675-682 (2014)
[Antimicrobial and cytostatic properties of 6-hydroxy-1,3-benzoxathiol-2-one (01 1)].
H Goeth et al.
Arzneimittel-Forschung, 19(8), 1298-1304 (1969-08-01)
Contact dermatitis to thioxolone.
J G Camarasa
Contact dermatitis, 7(4), 213-214 (1981-07-01)

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