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202444

Sigma-Aldrich

聚（乙二醇）

average MN 3,350, hydroxyl, powder

同義詞:

PEG

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About This Item

線性公式:
H(OCH2CH2)nOH
CAS號碼:
25322-68-3
MDL號碼:
MFCD00081839
分類程式碼代碼:
12352104
PubChem物質ID:
24852064
NACRES:
NA.23

產品名稱

聚（乙二醇）, average Mn 3,350, powder

形狀

powder

分子量

average Mn 3,350

pH值

4.5-7.5

黏度

90 cSt(210 °F) (99 °C)(lit.)

mp

54-58 °C (lit.)

密度

1.204 g/mL at 25 °C

Ω-end

hydroxyl

α-end

hydroxyl

SMILES 字串

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI 密鑰

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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相關類別

一般說明

聚乙二醇(PEG)是一种人造生物相容性惰性聚合物，由醚氧(-CH2-CH2-O-)重复单元构成。可通过氧乙烯的阴离子聚合反应制得。因具有非免疫原性和高水溶性，广泛用于生物和医学领域。

應用

聚乙二醇可用于修饰磁铁矿纳米粒子。在磁核上涂覆PEG外壳可使纳米粒子在保持磁性的前提下具备良好的稳定性。

PEG可用于修饰光催化TiO2纳米粉末，用于制造自清洁涂料。PEG涂覆的TiO2纳米粉末可通过温和条件制备，具有优异的胶体稳定性。

可用作交联剂，制备基于聚N-异丙基丙烯酰胺的热敏型可注射水凝胶。引入PEG提高了水凝胶的化学和机械性能，防止水凝胶在溶胀介质中溶解。这种水凝胶由于生物相容性和生物可降解性，广泛用于生物医学领域。

特點和優勢

  • 结构柔性高
  • 生物相容性
  • 水化能力高
  • 无任何空间位阻

其他說明

分子量：Mn 3,015-3,685

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儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number
MKCR1572
MKCQ0080
MKCQ0078
MKCN4138
MKCL5061

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Grant A Robinson et al.
Journal of neuroscience research, 94(7), 636-644 (2016-03-21)
Functional recovery following a peripheral nerve injury is made easier when regenerating axons correctly reinnervate their original targets. Polyethylene glycol (PEG) has recently been used in attempts to fuse severed peripheral axons during suture-based repair, but an analysis of target
Erinna F Lee et al.
Autophagy, 15(5), 785-795 (2019-01-11)
BECN1/Beclin 1 is a critical protein in the initiation of autophagosome formation. Recent studies have shown that phosphorylation of BECN1 by STK4/MST1 at threonine 108 (T108) within its BH3 domain blocks macroautophagy/autophagy by increasing BECN1 affinity for its negative regulators
Yixu Wang et al.
mSphere, 4(3) (2019-05-31)
Sporisorium scitamineum is the fungal pathogen causing severe sugarcane smut disease that leads to massive economic losses globally. S. scitamineum invades host cane by dikaryotic hyphae, formed after sexual mating of two haploid sporidia of opposite mating type. Therefore, mating/filamentation
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
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文章

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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