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192066

Sigma-Aldrich

聚甲基丙烯酸-2-羟乙酯

average Mv 300,000, crystalline

同義詞:

聚(2-HEMA), 聚-HEMA

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About This Item

線性公式:
(C6H10O3)n
CAS號碼:
25249-16-5
MDL號碼:
MFCD00084374
分類程式碼代碼:
12162002
PubChem物質ID:
24851526
NACRES:
NA.23

形狀

crystalline

分子量

average Mv 300,000

密度

1.15 g/mL at 25 °C (lit.)

SMILES 字串

CC(=C)C(=O)OCCO

InChI

1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3

InChI 密鑰

WOBHKFSMXKNTIM-UHFFFAOYSA-N

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相關類別

一般說明

固相的聚(2-羟乙酯甲基丙烯酸)(pHEMA)是脆性的，而pHEMA水凝胶是一种软材料。pHEMA水凝胶的玻璃化转变温度可通过增加基质中水的含量而降低。 pHEMA的大分子属性是通过聚合物链以及水合水分子之间氢键的非共价相互作用而得以表征的。 每一重复单元上羟基和羧基极性基团的存在使得该聚合物可与水相容。骨架上的疏水a-甲基可将水解稳定性传递给聚合物并提高聚合物基质的机械强度。

應用

pHEMA骨架被用于组织工程中。 它可作为金属离子的吸附剂被用于生物医学应用的水凝胶中。pHEMA已被用于如软性隐形眼镜、药物输送系统和肾脏透析膜等应用中。pHEMA的纳米粒子可作为抗癌和抗肿瘤药物的一种受控输送载体。

外觀

遇水膨胀聚合物。水凝胶。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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分析證明 (COA)

Lot/Batch Number
11118TH
10427LH
01126HH
01623BH
06012AH

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W E Roorda et al.
Pharmaceutical research, 5(11), 722-725 (1988-11-01)
The freezing and melting behavior of water in poly hydroxy ethyl methacrylate (pHEMA) hydrogels of different cross-linker and water contents was investigated in relation to the glass transition temperature (Tg) of the gels. After prolonged cooling at -15 degrees C
Fiber templating of poly (2-hydroxyethyl methacrylate) for neural tissue engineering
Flynn L,et al
Biomaterials, 24(23), 4265-4272 null
Yunfeng Li et al.
ACS applied materials & interfaces, 5(6), 2126-2132 (2013-02-23)
This paper presents a versatile way to prepare multiscale and gradient patterns of proteins. The protein patterns are fabricated by conjugating proteins covalently on patterns of polymer brush that are prepared by techniques combining colloidal lithography with photolithography, and two-step
Xiangling Meng et al.
Journal of biomedical materials research. Part A, 101(4), 1095-1102 (2012-09-26)
The objective of the present in vitro study was to investigate cardiomyocyte functions, specifically their adhesion and proliferation, on injectable scaffolds containing RNT (rosette nanotubes) and CNF (carbon nanofibers) in a pHEMA (poly(2-hydroxyethyl methacrylate)) hydrogel to determine their potential for
N Nogueira et al.
Journal of colloid and interface science, 385(1), 202-210 (2012-07-31)
The behavior of poly(2-hydroxyethyl methacrylate) (PHEMA) polymer monolayer spread on water was studied under various experimental conditions. The influence of subphase pH and temperature, compression speed, elapsed time from the deposit of the monolayer and the recording of the surface
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