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128635

Sigma-Aldrich

2-羟基乙基甲基丙烯酸酯

contains ≤250 ppm monomethyl ether hydroquinone as inhibitor, 97%

同義詞:

HEMA, 乙二醇单甲基丙烯酸酯, 甲基丙烯酸2-羟乙酯

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About This Item

線性公式:
CH2=C(CH3)COOCH2CH2OH
CAS號碼:
868-77-9
分子量：:
130.14
Beilstein:
1071583
EC號碼:
212-782-2
MDL號碼:
MFCD00002863
分類程式碼代碼:
12162002
PubChem物質ID:
24847870
NACRES:
NA.23

蒸汽密度

5 (vs air)

品質等級

200

蒸汽壓力

0.01 mmHg ( 25 °C)

化驗

97%

形狀

liquid

包含

≤250 ppm monomethyl ether hydroquinone as inhibitor

折射率

n20/D 1.453 (lit.)

bp

67 °C/3.5 mmHg (lit.)

密度

1.073 g/mL at 25 °C (lit.)

儲存溫度

2-8°C

SMILES 字串

CC(=C)C(=O)OCCO

InChI

1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3

InChI 密鑰

WOBHKFSMXKNTIM-UHFFFAOYSA-N

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相關類別

一般說明

甲基丙烯酸羟乙酯（HEMA）是第一个被用于合成生物医学用水凝胶的单体。通过与更多的亲水单体聚合，可增强HEMA的吸水膨胀性。HEMA在药物发现中被广泛应用。

應用

HEMA被用于合成生物功能性聚（甲基丙烯酸羟乙酯）（PHEMA）共聚物。它还被用于制备用于药物递送的PHEMA光响应膜、 基于HEMA/丙烯酰胺的特殊药物释放水凝胶 以及水溶性HEMA/甲基丙烯酸水凝胶。可研究HEMA对牙髓干细胞迁移（体外）的影响。

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H315,H317,H319

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

222.8 °F - closed cup

閃點（°C）

106 °C - closed cup

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分析證明 (COA)

Lot/Batch Number
STBK8107
STBK6268
MKCQ7377
STBK5038
WXBD6219V

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Preparation of Light-responsive Membranes by a Combined Surface Grafting and Postmodification Process.
Scholler K, et al.
Journal of Visualized Experiments, 85, e51680-e51680 (2014)
Drake W Williams et al.
Journal of endodontics, 39(9), 1156-1160 (2013-08-21)
Cell migration is an important step in pulpal wound healing. Although components in the resin-based dental materials are known to have adverse effects on pulp wound healing including proliferation and mineralization, their effects on cell migration have been scarcely examined.
Influence of the ionic character of a drug on its release rate from hydrogels based on 2-hydroxyethylmethacrylate and acrylamide synthesized by photopolymerization
Gomez ML, et al.
Express Polymer Letters, 6(30, 189-197 (2012)
Thomas J Dursch et al.
Biomaterials, 35(2), 620-629 (2013-10-24)
Two-photon confocal microscopy and back extraction with UV/Vis-absorption spectrophotometry quantify equilibrium partition coefficients, k, for six prototypical drugs in five soft-contact-lens-material hydrogels over a range of water contents from 40 to 92%. Partition coefficients were obtained for acetazolamide, caffeine, hydrocortisone
Loretta A Idowu et al.
Polymers, 11(3) (2019-04-10)
2-Hydroxyethyl methacrylate (HEMA) is an important component of many acrylic resins used in coatings formulations, as the functionality ensures that the chains participate in the cross-linking reactions required to form the final product. Hence, the knowledge of their radical copolymerization
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文章

Continuous Flow Manufacturing for Monomer Synthesis

The manufacture of monomers for use in ophthalmic applications is driven by the need for higher purity, improved reliability of manufacturing supply, but ultimately by the need for the increased comfort, convenience, and safety of contact lens wearers. Daily wear contact lenses have the potential to fill this need for many customers; however, their widespread use is constrained by higher costs compared to weekly- or monthly-based lenses. New approaches that improve cost structure and result in higher quality raw materials are needed to help make contact lenses more affordable and accelerate growth of the contact lens market.

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