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Merck
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重要文件

18805

Sigma-Aldrich

6-羟基吲哚

≥99.0% (GC)

同義詞:

吲哚醇

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About This Item

經驗公式(希爾表示法):
C8H7NO
CAS號碼:
分子量::
133.15
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

≥99.0% (GC)

形狀

solid

mp

126-132 °C

SMILES 字串

Oc1ccc2cc[nH]c2c1

InChI

1S/C8H7NO/c10-7-2-1-6-3-4-9-8(6)5-7/h1-5,9-10H

InChI 密鑰

XAWPKHNOFIWWNZ-UHFFFAOYSA-N

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應用

  • 作为反应物,用于制备色氨酸双加氧酶抑制剂吡啶基-乙烯基-吲哚——一种潜在的抗癌免疫调节剂
  • 作为反应物,用于不对称合成notoamide J——异戊烯化吲哚生物碱的潜在生物合成前体
  • 作为反应物,用于制备(喹啉基氧基甲基)异噁唑羧酸酯抗结核剂
  • 作为反应物,用于制备吲哚基(丙醇胺)衍生物——一种HIV抑制剂
  • 作为反应物,用于制备吲哚氧基乙酸衍生物——一种过氧化物酶体增殖物激活受体激动剂
  • 作为反应物,用于制备1-芳酰基吲哚-3-芳酰基吲哚类康瑞他汀A-4类似物——一种抗肿瘤剂和微管蛋白聚合抑制剂

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Jintae Lee et al.
Applied and environmental microbiology, 73(13), 4100-4109 (2007-05-08)
Since indole is present at up to 500 microM in the stationary phase and is an interspecies biofilm signal (J. Lee, A. Jayaraman, and T. K. Wood, BMC Microbiol. 7:42, 2007), we investigated hydroxyindoles as biofilm signals and found them
Damon Borg et al.
Journal of analytical toxicology, 41(1), 6-16 (2016-09-30)
Synthetic cannabinoids are a group of psychoactive compounds that mimic the effects of Δ9-tetrahydrocannabinol, the primary psychoactive constituent of marijuana (Cannabis sativa L). The Drug Enforcement Administration has classified many of the most common cannabinoids as Schedule 1 controlled substances.
Yoshimitsu Yamazaki et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 65(1-2), 49-54 (2010-04-02)
A recent study showed that N-acylserotonin derivatives have strong inhibitory activity against tyrosinase. To clarify the role of the 5-hydroxy group in the indole ring, 2-, 4-, 5-, 6-, and 7-hydroxyindole and 11 related compounds such as 5-hydroxyindan and 6-hydroxyquinoline
Martin Švidrnoch et al.
Talanta, 150, 568-576 (2016-02-04)
Perfluoroheptanoic acid was employed as a volatile micellar phase in background electrolyte for micellar electrokinetic chromatography-tandem mass spectrometry separation and determination of 15 selected naphthoyl- and phenylacetylindole- synthetic cannabinoids and main metabolites derived from JWH-018, JWH-019, JWH-073, JWH-200 and JWH-250.
Stefan W Toennes et al.
Drug testing and analysis, 10(4), 644-650 (2017-10-03)
Each year, synthetic cannabinoids occur in high numbers on the illicit drug market, but data on their detectability are rarely available. A pilot study was performed to assess adverse effects of JWH-018, which is one of the oldest and best

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