推薦產品
蒸汽密度
2.4 (vs air)
化驗
99%
形狀
liquid
折射率
n20/D 1.427 (lit.)
bp
93-95 °C (lit.)
密度
1.078 g/mL at 25 °C (lit.)
儲存溫度
2-8°C
SMILES 字串
c1cnoc1
InChI
1S/C3H3NO/c1-2-4-5-3-1/h1-3H
InChI 密鑰
CTAPFRYPJLPFDF-UHFFFAOYSA-N
尋找類似的產品？ 前往 產品比較指南
一般說明
Isoxazole are described as inhibitors of acetylcholinesterase (AChE). Isoxazole ligands bind to and inhibit the Sxc- antiporter.
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Inhibition of acetylcholinesterase (AChE) is a common treatment for early stages of Alzheimer's disease. In this study, nine isoxazoles derivatives were tested for their in-vitro AChE activity. The molecular docking showed the interaction of the compounds with the active site.
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Adam A Wallace et al.
The journal of physical chemistry. A, 125(1), 317-326 (2020-12-29)
Electron capture by the σ* LUMO of isoxazole triggers the dissociation of the O-N bond and the opening of the ring. Photodetachment of the resulting anion accesses a neutral structure, in which the O· and ·N bond fragments interact through
Sahaya Asirvatham et al.
Anti-inflammatory & anti-allergy agents in medicinal chemistry, 14(2), 128-137 (2015-08-13)
A series of newer 3-(4'-methoxyphenyl)-5-substituted phenylisoxazoles derivatives have been synthesized by reacting hydroxylamine hydrochloride with chalcones. The chalcones were formed by reacting different aromatic aldehydes with 4-methoxyacetophenone in presence of aqueos potassium hydroxide (KOH). The purity of all the synthesized
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