推薦產品
品質等級
化驗
99%
折射率
n20/D 1.537 (lit.)
bp
279 °C (lit.)
mp
6-7 °C (lit.)
密度
0.997 g/mL at 25 °C (lit.)
官能基
phenyl
SMILES 字串
C1CC(CCN1)Cc2ccccc2
InChI
1S/C12H17N/c1-2-4-11(5-3-1)10-12-6-8-13-9-7-12/h1-5,12-13H,6-10H2
InChI 密鑰
ABGXADJDTPFFSZ-UHFFFAOYSA-N
基因資訊
rat ... Htr2a(29595) , Htr2c(25187)
尋找類似的產品? 前往 產品比較指南
一般說明
4-苄基哌啶是多巴胺选择性释放剂。它是治疗可卡因成瘾的潜在候选药物。
應用
4-苄基哌啶被用于研究雄性B6C3F1小鼠和Sprague-Dawley大鼠的灌注肝脏中1,3-丁二烯及其氧化代谢产物的代谢。
用于合成以下物质的反应物:
- 抗增殖剂
- GABA吸收抑制剂
- 吡啶类
- 组胺 H3 拮抗剂
- 具有胆碱能和神经保护作用的多功能药物,可用于治疗阿尔茨海默氏症和神经血管疾病
- 通过亲核取代,发挥抗血清素、抗血小板、血液流变学、抗心律失常和抗氧化作用
生化/生理作用
4-苄基哌啶能够抑制大鼠脑单胺氧化酶-A和-B的活性。
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
233.6 °F - closed cup
閃點(°C)
112 °C - closed cup
個人防護裝備
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
客戶也查看了
Toxicological sciences : an official journal of the Society of Toxicology, 114(1), 25-37 (2009-12-17)
The industrial chemical 1,3-butadiene (BD) is a potent carcinogen in mice and a weak one in rats. This difference is generally related to species-specific burdens by the metabolites 1,2-epoxy-3-butene (EB), 1,2:3,4-diepoxybutane (DEB), and 3,4-epoxy-1,2-butanediol (EBD), which are all formed in
Neuroscience letters, 70(2), 255-260 (1986-10-08)
Inhibitory effects of some MPTP and MPP+ analogues on rat brain MAO activity were studied to further clarify the structure-activity relationships of MPTP neurotoxicity. Of the analogues tested, 4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine (CPTP), 4-(4-chlorobenzyl)-pyridine (CBP), 4-benzylpyridine (BPY) and 4-benzylpiperidine (BPIP) dose-dependently inhibited both
International journal of pharmaceutics, 550(1-2), 71-78 (2018-08-21)
The objective of our study was to develop a transdermal patch of 4-benzylpiperidine and to evaluate its in vitro transdermal permeation profile. Appropriate pressure sensitive adhesives and additives were selected based on solubility and slide crystallization studies. Release liners and
The Journal of pharmacology and experimental therapeutics, 329(1), 272-281 (2009-01-20)
Monoamine releasers constitute one class of drugs currently under investigation as potential agonist medications for the treatment of cocaine dependence. The efficacy and safety of monoamine releasers as candidate medications may be influenced in part by their relative potency to
我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務