PRKAR2A
protein kinase, cAMP-dependent, regulatory, type II, alpha
同義詞:
PKR2, PRKAR2
物種:
Human PRKAR2A (5576), Mouse Prkar2a (19087), Rat Prkar2a (29699), cow PRKAR2A (100139910), cow PRKAR2A (518399), sheep PRKAR2A (101118483), naked mole-rat Prkar2a (101706516), domestic guinea pig Prkar2a (100728915), dog PRKAR2A (100685147)
UniProtKB ID:
基因 ID:
- Human(5576) Summary: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER). [provided by RefSeq, Jul 2008]
- Mouse(19087) protein kinase, cAMP dependent regulatory, type II alpha
- Rat(29699) protein kinase, cAMP dependent regulatory, type II alpha
- cow(100139910) protein kinase, cAMP-dependent, regulatory, type II, alpha
- cow(518399) protein kinase, cAMP-dependent, regulatory, type II, alpha
- sheep(101118483) protein kinase, cAMP-dependent, regulatory, type II, alpha
- naked mole-rat(101706516) protein kinase, cAMP-dependent, regulatory, type II, alpha
- domestic guinea pig(100728915) protein kinase, cAMP-dependent, regulatory, type II, alpha
- dog(100685147) protein kinase, cAMP-dependent, regulatory, type II, alpha
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Antibodies
產品編號
描述
物種活性
應用
Anti-phospho PKA-RII (Ser96) Antibody, from rabbit, purified by affinity chromatography,
物種活性
human, mouse, rat
應用
western blot