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Merck

NOS1

nitric oxide synthase 1 (neuronal)

同義詞:
IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS
物種:
UniProtKB ID:
基因 ID:
  • Human(4842) Summary: The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011]
  • Mouse(18125) nitric oxide synthase 1, neuronal
  • Rat(24598) nitric oxide synthase 1, neuronal
  • Zebrafish(60658) nitric oxide synthase 1 (neuronal)
  • domestic cat(101100342) nitric oxide synthase 1 (neuronal)
  • cow(536132) nitric oxide synthase 1 (neuronal)
  • Horse(100051079) nitric oxide synthase 1 (neuronal)
  • dog(477498) nitric oxide synthase 1 (neuronal)
  • chicken(427721) nitric oxide synthase 1 (neuronal)
  • naked mole-rat(101711993) nitric oxide synthase 1 (neuronal)
  • Domestic Rabbit(100009243) nitric oxide synthase 1 (neuronal)
  • domestic guinea pig(100729682) nitric oxide synthase 1 (neuronal)

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Small Molecule - Antagonist

產品編號
描述
物種
(−)-Thalidomide, >98%, solid,
物種
human, mouse, rat
(+)-Thalidomide, ≥98% (HPLC), powder,
物種
human, mouse, rat
吡咯烷二硫代氨基甲酸铵, ~99%,
物種
human
褪黑素, powder, ≥98% (TLC),
物種
human
(±)-沙利度胺, ≥98%, powder,
物種
human, mouse, rat

Antibodies

產品編號
描述
物種活性
應用
抗硝基酪氨酸抗体, Upstate®, from rabbit,
物種活性
all
應用
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
抗硝基酪氨酸抗体, Chemicon®, from rabbit,
物種活性
all, human, mouse
應用
immunohistochemistry
western blot
抗硝基酪氨酸 兔抗, affinity isolated antibody, buffered aqueous solution,
物種活性
wide range
應用
ELISA
immunofluorescence

immunohistochemistry

microarray

western blot
一氧化氮合酶I抗体, serum, Chemicon®,
物種活性
human, monkey, mouse, rat, sheep
應用
immunohistochemistry
western blot
Anti-Nitrotyrosine Antibody, clone 1A6, Alexa Fluor 555 conjugate, clone 1A6, Upstate®, from mouse,
物種活性
vertebrates
應用
flow cytometry
western blot

Small Molecule - Inhibitor

產品編號
描述
物種
亚精胺 三盐酸盐, ≥98% (TLC),
物種
human
4-硝基儿茶酚, ≥96.0%,
物種
rat
5-甲基-2-硝基苯胺, 95%,
物種
rat
2,6-二--丁基-4-甲基苯酚, ≥99.0% (GC), powder,
物種
rat, human
L-精氨酸, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%,
物種
rat, human

Kits

產品編號
描述
物種
一氧化氮合酶检测系统,荧光法, sufficient for 200 reactions,
物種
human

Small Molecule - Precursor

產品編號
描述
物種
L-精氨酸, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%,
物種
rat, human
L-精氨酸, ,
物種
rat, human
L-精氨酸, 99%, FCC, FG,
物種
rat, human
L-精氨酸, reagent grade, ≥98%,
物種
rat, human
L-精氨酸, BioUltra, ≥99.5% (NT),
物種
rat, human