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Sigma-Aldrich

Anti-Nitrotyrosine Antibody, clone 1A6, Alexa Fluor 555 conjugate

clone 1A6, Upstate®, from mouse

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

共軛

ALEXA FLUOR 555

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

1A6, monoclonal

物種活性

vertebrates

製造商/商標名

Upstate®

技術

flow cytometry: suitable
western blot: suitable

同型

IgG2bκ

運輸包裝

wet ice

目標翻譯後修改

nitration (Tyr)

基因資訊

human ... NOS1(4842)

特異性

recognizes nitrated protein

免疫原

Nitrated KLH

應用

Anti-Nitrotyrosine Antibody, clone 1A6, Alexa Fluor 555 conjugate is an antibody against Nitrotyrosine for use in FC & WB.
Research Category
Neuroscience
Research Sub Category
Oxidative Stress

品質

Routinely evaluated by immunoblot.

標靶描述

The molecular weight is related to the nitrated protein

外觀

Protein G Purified

儲存和穩定性

1 year at 4°C from date of shipment

法律資訊

ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Alexa Fluor is a registered trademark of Molecular Probes, Inc.

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儲存類別代碼

10 - Combustible liquids


分析證明 (COA)

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Biological significance of nitric oxide-mediated protein modifications.
Gow, Andrew J, et al.
American Journal of Physiology. Lung Cellular and Molecular Physiology, 287, L262-L268 (2004)
Ming-Hui Zou et al.
The Journal of clinical investigation, 109(6), 817-826 (2002-03-20)
Nitric oxide (NO) is produced by NO synthase (NOS) in many cells and plays important roles in the neuronal, muscular, cardiovascular, and immune systems. In various disease conditions, all three types of NOS (neuronal, inducible, and endothelial) are reported to
Zarema Balafanova et al.
The Journal of biological chemistry, 277(17), 15021-15027 (2002-02-13)
Activation of protein kinase C (PKC) epsilon by nitric oxide (NO) has been implicated in the development of cardioprotection. However, the cellular mechanisms underlying the activation of PKCepsilon by NO remain largely unknown. Nitration of protein tyrosine residues has been
J Torreilles et al.
BMC immunology, 2, 1-1 (2001-03-07)
Peroxynitrite is increasingly proposed as a contributor to defence system in marine bivalve. It can be formed by combination of superoxide and nitric oxide, and can react with tyrosine residues of proteins giving rise to 3-nitrotyrosine. The present article describes
C Ayata et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 17(18), 6908-6917 (1997-09-15)
We investigated the role of neuronal (type I) nitric oxide synthase (nNOS) in NMDA-mediated excitotoxicity in wild-type (SV129 and C57BL/6J) and type I NOS knock-out (nNOS-/-) mice and examined its relationship to apoptosis. Excitotoxic lesions were produced by intrastriatal stereotactic

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