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IMPDH2

IMP (inosine 5'-monophosphate) dehydrogenase 2

同義詞:
IMPD2, IMPDH-II
物種:
UniProtKB ID:
基因 ID:
  • Human(3615) Summary: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
  • Mouse(23918) inosine 5'-phosphate dehydrogenase 2
  • Rat(301005) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Zebrafish(317745) IMP (inosine monophosphate) dehydrogenase 2
  • Horse(100063255) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • cow(511969) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • domestic cat(101080693) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • chicken(416058) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • dog(476630) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • domestic guinea pig(100730768) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • naked mole-rat(101701391) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • sheep(101107823) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Domestic Rabbit(100355621) IMP (inosine 5'-monophosphate) dehydrogenase 2

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Antibodies

產品編號
描述
物種活性
應用
Anti-IMPDH2 Mouse mAb (1E12-B6), liquid, clone 1E12-B6, Calbiochem®,
物種活性
human
應用
Monoclonal Anti-IMPDH2 antibody produced in mouse, clone 1E12-B6, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunoprecipitation (IP)

western blot
Anti-IMPDH2 antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
應用
western blot

Small Molecule - Inhibitor

產品編號
描述
物種
还原型 β-烟酰胺腺嘌呤二核苷酸 二钾盐, ,
物種
human
6-硫代鸟嘌呤, ≥98%,
物種
human
霉酚酸, ≥98%,
物種
human
利巴韦林, antiviral,
物種
human
霉酚酸, powder, BioReagent, suitable for cell culture,
物種
human

Proteins

產品編號
描述
物種
Inosine Monophosphate Dehydrogenase Type II human, recombinant, expressed in E. coli,
物種
human