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Merck

GRIN2B

glutamate receptor, ionotropic, N-methyl D-aspartate 2B

同義詞:
GluN2B, MRD6, NMDAR2B, NR2B, hNR3
物種:
UniProtKB ID:
基因 ID:
  • Human(2904) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq, Jul 2008]
  • Mouse(14812) glutamate receptor, ionotropic, NMDA2B (epsilon 2)
  • Rat(24410) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • chicken(417965) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • dog(494009) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • domestic cat(101094356) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • Horse(100063746) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • cow(537804) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • domestic guinea pig(100731840) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • naked mole-rat(101723091) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • sheep(101118179) glutamate receptor, ionotropic, N-methyl D-aspartate 2B

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Small Molecule - Agonist

產品編號
描述
物種
Reversin 205, ≥98% (HPLC), film,
物種
mouse, rat, human
D-环丝氨酸, synthetic,
物種
human
右美沙芬 氢溴酸盐 一水合物, ≥99% (TLC),
物種
human
N-甲基- D -天冬氨酸, ≥98% (TLC), solid,
物種
human, rat
(S)-AMPA, ≥97%,
物種
mouse, human, rat

Small Molecule - Allosteric Modulator

產品編號
描述
物種
盐酸氯胺酮标准液 盐酸盐 溶液, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
物種
human
(±)-氯胺酮 盐酸盐, solid,
物種
human
S-(+)-Ketamine hydrochloride, ,
物種
human
(±)-氯胺酮 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物種
human
阿坎酸钙, ≥98% (HPLC), powder,
物種
human

Small Molecule - Antagonist

產品編號
描述
物種
DL-2-氨基己二酸, ≥99%,
物種
rat
2-苯基喹啉, 99%,
物種
rat
Ro 25-6981 盐酸盐 水合物, ≥98% (HPLC), powder,
物種
human
Ro 8-4304, solid,
物種
human
精胺, ≥97%,
物種
rat, human

Antibodies

產品編號
描述
物種活性
應用
PhosphoDetect Anti-NMDA NR2B (pTyr¹⁴⁷²) Rabbit pAb, liquid, Calbiochem®,
物種活性
rat
應用
Anti-GRIN2B antibody produced in rabbit, affinity isolated antibody,
物種活性
horse, human, mouse, rabbit, rat
應用
immunohistochemistry
western blot
Anti-NMDAR2B antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
western blot
抗-NR2B抗体,克隆BWJHL, clone BWJHL, Upstate®, from mouse,
物種活性
human, rat
應用
western blot
抗-NMDAR2B抗体,磷酸Tyr 1472, Chemicon®, from rabbit,
物種活性
rat
應用
western blot

Small Molecule - Blocker

產品編號
描述
物種
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
物種
human
胍丁胺 硫酸盐, ≥97%, powder,
物種
human
奥芬那君 盐酸盐, ≥98.0% (AT),
物種
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物種
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物種
human

Small Molecule - Inhibitor

產品編號
描述
物種
喷他脒 羟乙基磺酸盐, powder,
物種
human
奥芬那君 盐酸盐, ≥98.0% (AT),
物種
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物種
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物種
human
L-谷氨酸, ReagentPlus®, ≥99% (HPLC),
物種
rat, human

esiRNA

產品編號
描述
物種
MISSION® esiRNA, targeting human GRIN2B,
物種
human