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Key Documents

R1401

Sigma-Aldrich

Reversin 205

≥98% (HPLC), film

同義詞:

[Boc-Glu(Obzl)]2-Lys-Ome

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About This Item

經驗公式(希爾表示法):
C41H58N4O12
CAS號碼:
分子量::
798.92
MDL號碼:
分類程式碼代碼:
12161501
PubChem物質ID:
NACRES:
NA.47

化驗

≥98% (HPLC)

形狀

film

儲存條件

desiccated

顏色

colorless

mp

101-102 °C

溶解度

DMSO or ethanol: soluble (Insoluble in water)

儲存溫度

−20°C

SMILES 字串

COC(=O)[C@H](CCCCNC(=O)[C@H](CCC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C)NC(=O)[C@H](CCC(=O)OCc2ccccc2)NC(=O)OC(C)(C)C

InChI

1S/C41H58N4O12/c1-40(2,3)56-38(51)44-30(21-23-33(46)54-26-28-16-10-8-11-17-28)35(48)42-25-15-14-20-32(37(50)53-7)43-36(49)31(45-39(52)57-41(4,5)6)22-24-34(47)55-27-29-18-12-9-13-19-29/h8-13,16-19,30-32H,14-15,20-27H2,1-7H3,(H,42,48)(H,43,49)(H,44,51)(H,45,52)/t30-,31-,32-/m0/s1

InChI 密鑰

BRVAQYBFHAIYLQ-CPCREDONSA-N

基因資訊

human ... GRIN2B(2904)
mouse ... GRIN2B(14812)
rat ... GRIN2B(24410)

一般說明

Reversin 205 is a hydrophobic peptide.

應用

Reversin 205 has been used to determine the activity of P-glycoprotein in human retinal pigment epithelium.

生化/生理作用

Peptide chemosensitizer, inhibitor of P-glycoprotein.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems, and intact cells.
Sharom FJ
Biochemical Pharmacology, 58(4), 571-586 (1999)
P-glycoprotein expression in human retinal pigment epithelium
Brian G
Molecular Vision, 8 (2002)

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