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Merck

GRIN1

glutamate receptor, ionotropic, N-methyl D-aspartate 1

同義詞:
GluN1, MRD8, NMDA1, NMDAR1, NR1
物種:
UniProtKB ID:
基因 ID:
  • Human(2902) Summary: The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
  • Mouse(14810) glutamate receptor, ionotropic, NMDA1 (zeta 1)
  • Rat(24408) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • chicken(404296) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • dog(494007) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • Horse(100059861) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • cow(100336579) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • domestic guinea pig(100301989) glutamate receptor, ionotropic, NMDA1 (zeta 1)
  • naked mole-rat(101720185) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • sheep(443281) glutamate receptor, ionotropic, N-methyl D-aspartate 1

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Small Molecule - Agonist

產品編號
描述
物種
D -丝氨酸, ≥98% (TLC),
物種
human
精胺 四盐酸盐, powder or crystals,
物種
human
牛磺酸, ≥99%,
物種
human, rat
D-环丝氨酸, synthetic,
物種
human
右美沙芬 氢溴酸盐 一水合物, ≥99% (TLC),
物種
human

Small Molecule - Allosteric Modulator

產品編號
描述
物種
盐酸氯胺酮标准液 盐酸盐 溶液, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
物種
human
(±)-氯胺酮 盐酸盐, solid,
物種
human
S-(+)-Ketamine hydrochloride, ,
物種
human
(±)-氯胺酮 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物種
human
阿坎酸钙, ≥98% (HPLC), powder,
物種
human

Small Molecule - Antagonist

產品編號
描述
物種
CP-101,606, ≥98% (HPLC),
物種
human
MDL 105,519, ≥98% (HPLC), solid,
物種
rat, human
右啡烷 酒石酸酯, powder,
物種
human
艾芬地尔 (+)-酒石酸盐, ,
物種
human
魁蛤素 硫酸盐, ,
物種
human

Antibodies

產品編號
描述
物種活性
應用
抗-NMDAR1 兔抗, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-Glun1-Nr1 antibody produced in mouse, clone S308-48, purified immunoglobulin,
物種活性
human, mouse, rat
應用
immunocytochemistry
immunohistochemistry

western blot
Anti-NMDA Receptor 1/GRIN1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
human, mouse
應用
ELISA
immunofluorescence
Anti-NMDAR1 antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry

western blot
Anti-phospho-NMDAR1 (pSer896) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry

western blot

Small Molecule - Blocker

產品編號
描述
物種
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
物種
human
胍丁胺 硫酸盐, ≥97%, powder,
物種
human
奥芬那君 盐酸盐, ≥98.0% (AT),
物種
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物種
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物種
human

Small Molecule - Inhibitor

產品編號
描述
物種
牛磺酸, ≥99%,
物種
human, rat
喷他脒 羟乙基磺酸盐, powder,
物種
human
奥芬那君 盐酸盐, ≥98.0% (AT),
物種
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物種
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物種
human

esiRNA

產品編號
描述
物種
MISSION® esiRNA, targeting human GRIN1,
物種
human