CASP3
caspase 3, apoptosis-related cysteine peptidase
同義詞:
CPP32, CPP32B, SCA-1
物種:
Human CASP3 (836), Mouse Casp3 (12367), Rat Casp3 (25402), sheep CASP3 (443031), Domestic Rabbit CASP3 (100008840), domestic guinea pig Casp3 (100718309), naked mole-rat Casp3 (101712867), chicken CASP3 (395476), domestic cat CASP3 (493932), cow CASP3 (408016) ...更多
UniProtKB ID:
基因 ID:
- Human(836) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
- Mouse(12367) caspase 3
- Rat(25402) caspase 3
- sheep(443031) caspase 3, apoptosis-related cysteine peptidase
- Domestic Rabbit(100008840) caspase 3, apoptosis-related cysteine peptidase
- domestic guinea pig(100718309) caspase 3, apoptosis-related cysteine peptidase
- naked mole-rat(101712867) caspase 3, apoptosis-related cysteine peptidase
- chicken(395476) caspase 3, apoptosis-related cysteine peptidase
- domestic cat(493932) caspase 3, apoptosis-related cysteine peptidase
- cow(408016) caspase 3, apoptosis-related cysteine peptidase
- Horse(100034083) caspase 3, apoptosis-related cysteine peptidase
- dog(403567) caspase 3, apoptosis-related cysteine peptidase
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Antibodies
產品編號
描述
物種活性
應用
抗胱天蛋白酶3抗体，活性（裂解）形式, Chemicon®, from rabbit,
物種活性
human, mouse, rat
應用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CASP3 (p17, Cleaved-Asp175) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
western blot
western blot
抗-Caspase 3抗体, Upstate®, from rabbit,
物種活性
human, mouse, rat
應用
immunohistochemistry
western blot
western blot
抗半胱天冬酶3（活性形式）抗体，克隆3D9.3, clone 3D9.3, from mouse,
物種活性
human
應用
flow cytometry
immunocytochemistry
western blot
immunocytochemistry
western blot
Monoclonal Anti-Caspase 3 antibody produced in mouse, clone 84803.111, purified immunoglobulin, lyophilized powder,
物種活性
human
應用
western blot
Small Molecule - Inhibitor
Kits
產品編號
描述
物種
Caspase 3 Colorimetric Activity Assay Kit, DEVD, Caspase-3 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the sequence DEVD.,
物種
human
CaspaTag Caspase 3,7 In Situ Assay Kit, Fluorescein, The CaspaTag Caspase-3/7 In Situ Assay Kit, Fluorescein for Flow Cytometry is a fluorescent-based assay for detection of active caspase-3 or caspase-7 in cells undergoing apoptosis.,
物種
human
Caspase 3 Colorimetric Activity Assay Kit, DEVD, Caspase-3 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the sequence DEVD.,
物種
human
CaspaTag Caspase 3,7 In Situ Assay Kit, Fluorescein, The In Situ Caspase Detection Kit for Flow Cytometry use a novel approach to detect active caspases. The methodology is based on Fluorochrome Inhibitors of Caspases (FLICA).,
物種
human
Proteins
產品編號
描述
物種
半胱天冬酶 3 人, ≥90% (SDS-PAGE), recombinant, expressed in E. coli (C-terminal histidine-tagged), buffered aqueous glycerol solution, ≥1.0 units/mg protein,
物種
human
esiRNA
產品編號
描述
物種