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Key Documents

SAB2900425

Sigma-Aldrich

Anti-GLP1R antibody produced in rabbit

affinity isolated antibody

Synonym(s):

GLP-1 receptor, GLP-1-R, GLP-1R, GLP-I receptor, GLP1R, Glp1 receptor

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

immunohistochemistry: 8 μg/mL

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GLP1R(2740)

General description

ASCT1 functions primarily as a neutral amino acid exchanger. ASCT 1-mediated transport requires the presence of sodium ions but ASCT1 mediates only homo- and hetero exchange of amino acids and is insensitive to K+. The properties of ASCT1 suggest that it may function to equilibrate different pools of neutral amino acids and provide a mechanism to link amino acid concentration gradients. ASCT1 expression has been found at varying levels in every tissue examined.

Immunogen

Synthetic 20 amino acid peptide from C-terminus of human GLP1R. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Horse (100%); Hamster, Elephant, Pig (95%); Mouse, Rat, Dog, Panda, Rabbit, Turkey, Chicken (90%); Bat, Opossum (85%); Lizard (80%).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate-buffered saline containing less than 0.1% sodium azide.
Supplied at 1 mg/ml

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Qian Zhang et al.
BMC complementary and alternative medicine, 14, 188-188 (2014-06-11)
Berberine is known to improve glucose and lipid metabolism disorders, but it poorly absorbed into the blood stream from the gut. Therefore, the exact underlying mechanism for berberine is still unknown. In this study, we investigated the effect of berberine
Yichao Fan et al.
Molecular vision, 20, 1557-1568 (2014-12-10)
Exendin-4 (E4), a long-acting agonist of the hormone glucagon-like peptide 1 receptor (GLP-1R), is administered to treat type II diabetes in the clinical setting and also shows a neuroprotective effect. Our previous studies demonstrated its protective effect in early experimental
Sze Wa Chan et al.
Neuropharmacology, 83, 71-78 (2014-04-15)
The use of glucagon-like peptide-1 (7-36) amide (GLP-1) receptor agonists for the treatment of type 2 diabetes mellitus is commonly associated with nausea and vomiting. Previous studies using Suncus murinus revealed that the GLP-1 receptor agonist, exendin-4, induces emesis via
Olga Bloch et al.
Journal of diabetes research, 2015, 561353-561353 (2015-04-22)
T2DM patients demonstrate reduced GLP-1 receptor (GLP-1R) expression in their gastric glands. Whether induced T2DM and T1DM differently affect the gastric GLP-1R expression is not known. This study assessed extrapancreatic GLP-1R system in glandular stomach of rodents with different types
Bin Zhu et al.
Anesthesiology, 121(4), 835-851 (2014-09-24)
Lamiophlomis rotata is an orally available Tibetan herb prescribed for the management of pain, with shanzhiside methylester (SM) and 8-O-acetyl-SM as quality control ingredients. This study aimed to evaluate the antinociceptive properties of L. rotata, determine whether SM and 8-O-acetyl-SM

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