P0869

Monoclonal Anti-Peroxisome Proliferator Activated Receptor α antibody produced in mouse

~1 mg/mL, clone 3B6/PPAR, purified immunoglobulin, buffered aqueous solution

• Synonym(s): Anti-PPARα
• MDL number: MFCD01092469
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 200
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 3B6/PPAR, monoclonal
• form: buffered aqueous solution
• species reactivity: mouse, rat, human
• concentration: ~1 mg/mL
• technique(s): western blot: 2-5 μg/mL using human, mouse and rat
• isotype: IgG2b
• UniProt accession no.: Q07869
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... PPARA(5465) ; mouse ... Ppara(19013) ; rat ... Ppara(25747)

Description

General description

Peroxisome proliferator-activated receptors (PPARs) are a group of closely related nuclear receptors. Three PPAR isotypes have been identified: α,β (also called NUC1) and γ. PPARa mRNA is expressed most in brown adipose tissue, heart, liver and kidney in rats. The gene encoding PPARα is localized on human chromosome 22q12-q13.1 and rat chromosome 7q34.

Immunogen

purified recombinant PPARα protein.

Biochem/physiol Actions

Peroxisome proliferator-activated receptors (PPARs) may be involved in chronic diseases such as diabetes, obesity, atherosclerosis and cancer. PPARα has a protective function in fatty acids overload associated tubular injury. The enzyme also has a role in fatty acid oxidation and metabolism.

Physical form

Solution in phosphate buffered saline containing 1 mg/ml bovine serum albumin and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable