Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

A111

Sigma-Aldrich

Adenosine amine congener hydrate

solid, ≥98% (HPLC)

Synonym(s):

ADAC, N6-[4-[[[4-[[[(2-Aminoethyl)amino]carbonyl]methyl]-anilino]carbonyl]methyl]phenyl]adenosine hydrate

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C28H32N8O6 · xH2O
CAS Number:
96760-69-9
Molecular Weight:
576.60 (anhydrous basis)
MDL number:
MFCD11045962
UNSPSC Code:
12352202
PubChem Substance ID:
24890507
NACRES:
NA.77

Assay

≥98% (HPLC)

form

solid

storage condition

protect from light

color

white

solubility

0.1 M acetic acid: 12 mM
DMSO: soluble

SMILES string

O.NCCNC(=O)Cc1ccc(NC(=O)Cc2ccc(Nc3ncnc4n(cnc34)[C@@H]5O[C@H](CO)[C@@H](O)[C@H]5O)cc2)cc1

InChI

1S/C28H32N8O6.H2O/c29-9-10-30-21(38)11-16-1-5-18(6-2-16)34-22(39)12-17-3-7-19(8-4-17)35-26-23-27(32-14-31-26)36(15-33-23)28-25(41)24(40)20(13-37)42-28;/h1-8,14-15,20,24-25,28,37,40-41H,9-13,29H2,(H,30,38)(H,34,39)(H,31,32,35);1H2/t20-,24-,25-,28-;/m1./s1

InChI key

KPSYUNGHYKDIMQ-LWOJYUBXSA-N

Gene Information

rat ... Adora1(29290)

Biochem/physiol Actions

Potent aqueous-soluble A1 adenosine receptor agonist.

Features and Benefits

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Caution

Photosensitive

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
067K4712

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Kai Ji et al.
Radiation oncology (London, England), 7, 200-200 (2012-11-29)
To quantify the incidental irradiation dose to esophageal lymph node stations when irradiating T1-4N0M0 thoracic esophageal squamous cell carcinoma (ESCC) patients with a dose of 60 Gy/30f. Thirty-nine patients with medically inoperable T1-4N0M0 thoracic ESCC were treated with three-dimensional conformal
Savvas Frangos et al.
European journal of nuclear medicine and molecular imaging, 42(13), 2045-2055 (2015-08-02)
We determined the reasons for radioiodine thyroid remnant ablation, and the procedure's necessity based on postsurgical remnant size, in patients with putatively "low-intermediate-risk" differentiated thyroid carcinoma (DTC). We identified key clinicopathological, treatment and remnant characteristics, and factors associated with remnant
K A Jacobson et al.
FEBS letters, 225(1-2), 97-102 (1987-12-10)
Chemically functionalized congeners of N6-phenyladenosine and 1,3-dipropyl-8-phenylxanthine have been covalently coupled to fatty acids, diglycerides, and a phospholipid. The lipid-drug conjugates inhibit R-[3H]-phenylisopropyladenosine binding to A1-adenosine receptors in rat cerebral cortex membranes. A xanthine-phosphatidylethanolamine conjugate bound with a Ki value
Miguel Rodriguez et al.
Radiation oncology (London, England), 13(1), 256-256 (2018-12-29)
PRIMO is a dose verification system based on the general-purpose Monte Carlo radiation transport code PENELOPE, which implements an accurate physics model of the interaction cross sections and the radiation transport process but with low computational efficiency as compared with
David Blum et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 22(20), 9122-9133 (2002-10-22)
Huntington's disease is a genetic neurodegenerative disorder characterized clinically by both motor and cognitive impairments and striatal lesions. At present, there are no pharmacological treatments able to prevent or slow its development. In the present study, we report the neuroprotective
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service