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O-902

Oxazepam solution

Name: Oxazepam solution
Brand: CERILLIAN

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₁₁ClN₂O₂

CAS Number:

604-75-1

Molecular Weight:

286.71

EC Number:

200-659-6

MDL number:

MFCD00057903

UNSPSC Code:

41116107

PubChem Substance ID:

329818934

NACRES:

NA.24

grade

certified reference material

Quality Level

300

form

liquid

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant^®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

concentration

1 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

OC1N=C(c2ccccc2)c3cc(Cl)ccc3NC1=O

InChI

1S/C15H11ClN2O2/c16-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)18-15(20)14(19)17-12/h1-8,15,20H,(H,17,19)

InChI key

ADIMAYPTOBDMTL-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

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Related Categories

Certified Reference Materials

Controlled Substances & Illicit Drug Standards

Pharmaceuticals, Illicit Drugs & Alcohol Standards

General description

A Certified Spiking Solution^® used as a starting material in calibrators and controls for GC/MS or LC/MS testing applications in pain prescription monitoring, clinical toxicology, or forensic analysis. Oxazepam is a benzodiazepine drug used to treat anxiety and insomnia and to control the symptoms of alcohol withdrawal.

Application

Oxazepam research solution: Oxazepam is widely used in pharmaceutical research to study its effects and metabolic pathways in the body. Advanced LC-MS/MS methods have been developed to determine oxazepam in biological samples, providing precise data on its pharmacokinetics and pharmacodynamics (Matsuo et al., 2024).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTIONS is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.

Description

Pricing

Signal Word

Danger

Hazard Statements

H225 - H301 + H311 + H331 - H370

Precautionary Statements

P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Gene expression and mutation assessment provide clues of genetic and epigenetic mechanisms in liver tumors of oxazepam-exposed mice.

S A Lahousse et al.

Veterinary pathology, 48(4), 875-884 (2010-12-15)

Liver tumors from a previous National Toxicology Program study were examined using global gene expression and mutation analysis to define the mechanisms of carcinogenesis in mice exposed to oxazepam. Five hepatocellular adenomas and 5 hepatocellular carcinomas from male B6C3F1 mice

Laboratory and clinical evaluation of on-site urine drug testing.

Olof Beck et al.

Scandinavian journal of clinical and laboratory investigation, 74(8), 681-686 (2014-07-22)

Products for on-site urine drug testing offer the possibility to perform screening for drugs of abuse directly at the point-of-care. This is a well-established routine in emergency and dependency clinics but further evaluation of performance is needed due to inherent

Effects of oxazepam on affective perception, recognition, and event-related potentials.

Jonas K Olofsson et al.

Psychopharmacology, 215(2), 301-309 (2011-01-05)

Little is known about how rapid electrocortical responses (event-related potentials; ERPs) to affective pictures are modulated by benzodiazepine agonists. The present study investigated effects of oxazepam (20 mg p.o.) on behavioral measures and ERPs associated with affective picture processing during

The clinical pharmacology of oxazepam.

M H Lader

Acta psychiatrica Scandinavica. Supplementum, (274)(274), 89-93 (1978-01-01)

The benzodiazepines have been available now for about 15 years but new aspects of their actions are being elucidated all the time. Oxazepam has a short half-life and inactive metabolites and therefore differs from most other benzodiazepines. Some aspects of

ABOP, the automatic patient information leaflet optimizer: evaluation of a tool in development.

Maarten Charles J Franck et al.

Patient education and counseling, 83(3), 411-416 (2011-05-31)

We developed a semi-automated leaflet optimizer (ABOP) to improve the readability of Dutch patient information leaflets (PILs). Our aim was to assess whether or not revisions made with ABOP have an effect on traceability and comprehension of PIL information. Two

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-THC solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material

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